Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Bone Marrow Phagocytosis in Sarcoidosis

Bone Marrow Phagocytosis in Sarcoidosis Abstract • The phagocytic activity of the bone marrow monocytes and macrophages was studied in 22 patients with sarcoidosis, 28 patients with Hodgkin's and non-Hodgkin's malignant neoplasms, and 14 controls. Although phagocytosis of RBCs and WBCs and platelets was seen in all bone marrow specimens, the activity was considerably increased in some patients with stage I and stage II sarcoidosis. This observation may reflect the presence of an unusual host response to unknown antigens in patients with sarcoidosis. (Arch Intern Med 1982;142:479-480) References 1. Miale GB: Laboratory Medicine Hematology . St Louis, CV Mosby Co, 1977, p 166. 2. Bessis M: Blood Smears Reinterpreted . Berlin, Springer-Verlag, 1977, p 157. 3. Kitchens CS: Clinical observations of human bone marrow macrophages. Medicine 1977;56:503-513.Crossref 4. Cream JJ: Prednisone-induced granulocytosis. Br J Haematol 1968;15:259-267.Crossref 5. Horster JA: Phagozytose von Blutzellverstufen im Knochenmarts bei Agranulozytose und 'ahnlichen erbranbunger.' Dtsch Med Wochenschr 1957;82:1786-1789.Crossref 6. Marton PF: Erythrophagocytosis in the human bone marrow as disclosed by iliac bone biopsies. Scand J Haematol 1975;14:153-159.Crossref 7. Kohout J: Macrophage reactivity in skin window of sarcoidosis patients. Ann NY Acad Sci 1976;278:201-203.Crossref 8. Douglas SD, Schmidt ME, Sietzbach LE: Monocyte receptor activity in normal individuals and patients with sarcoidosis. Immunol Commun 1972;1:25-38. 9. Douglas SD, Daughaday CC: Kinetics of monocyte receptor activity for immunoproteins in patients with sarcoidosis. Ann NY Acad Sci 1976;278:190-200.Crossref 10. Lessin LS, Bessis M, Douglas SD: Morphology of Monocytes and Macrophages , in Williams WJ, Beutler E, Erslev AJ, et al (eds): Hematology . New York, McGraw-Hill Book Co, 1977, pp 851-860. 11. James DG: Modern concepts of sarcoidosis. Chest 1973;64:675-677.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Bone Marrow Phagocytosis in Sarcoidosis

Loading next page...
 
/lp/american-medical-association/bone-marrow-phagocytosis-in-sarcoidosis-AbvP0IuU0R
Publisher
American Medical Association
Copyright
Copyright © 1982 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1982.00340160063015
Publisher site
See Article on Publisher Site

Abstract

Abstract • The phagocytic activity of the bone marrow monocytes and macrophages was studied in 22 patients with sarcoidosis, 28 patients with Hodgkin's and non-Hodgkin's malignant neoplasms, and 14 controls. Although phagocytosis of RBCs and WBCs and platelets was seen in all bone marrow specimens, the activity was considerably increased in some patients with stage I and stage II sarcoidosis. This observation may reflect the presence of an unusual host response to unknown antigens in patients with sarcoidosis. (Arch Intern Med 1982;142:479-480) References 1. Miale GB: Laboratory Medicine Hematology . St Louis, CV Mosby Co, 1977, p 166. 2. Bessis M: Blood Smears Reinterpreted . Berlin, Springer-Verlag, 1977, p 157. 3. Kitchens CS: Clinical observations of human bone marrow macrophages. Medicine 1977;56:503-513.Crossref 4. Cream JJ: Prednisone-induced granulocytosis. Br J Haematol 1968;15:259-267.Crossref 5. Horster JA: Phagozytose von Blutzellverstufen im Knochenmarts bei Agranulozytose und 'ahnlichen erbranbunger.' Dtsch Med Wochenschr 1957;82:1786-1789.Crossref 6. Marton PF: Erythrophagocytosis in the human bone marrow as disclosed by iliac bone biopsies. Scand J Haematol 1975;14:153-159.Crossref 7. Kohout J: Macrophage reactivity in skin window of sarcoidosis patients. Ann NY Acad Sci 1976;278:201-203.Crossref 8. Douglas SD, Schmidt ME, Sietzbach LE: Monocyte receptor activity in normal individuals and patients with sarcoidosis. Immunol Commun 1972;1:25-38. 9. Douglas SD, Daughaday CC: Kinetics of monocyte receptor activity for immunoproteins in patients with sarcoidosis. Ann NY Acad Sci 1976;278:190-200.Crossref 10. Lessin LS, Bessis M, Douglas SD: Morphology of Monocytes and Macrophages , in Williams WJ, Beutler E, Erslev AJ, et al (eds): Hematology . New York, McGraw-Hill Book Co, 1977, pp 851-860. 11. James DG: Modern concepts of sarcoidosis. Chest 1973;64:675-677.Crossref

Journal

Archives of Internal MedicineAmerican Medical Association

Published: Mar 1, 1982

References