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ARTICLE Body Mass Index and Timing of Pubertal Initiation in Boys Joyce M. Lee, MD, MPH; Niko Kaciroti, PhD; Danielle Appugliese, MPH; Robert F. Corwyn, PhD; Robert H. Bradley, PhD; Julie C. Lumeng, MD Objective: To examine the association between body Main Outcome Measure: Onset of puberty at age 11.5 mass index (BMI [calculated as weight in kilograms di- years as measured by Tanner genitalia staging. vided by height in meters squared]) and timing of pu- bertal onset in a population-based sample of US boys. Results: Boys in the highest BMI trajectory (mean BMI z score at age 11.5 years, 1.84) had a greater relative risk Design: Longitudinal prospective study. of being prepubertal compared with boys in the lowest BMI trajectory (mean BMI z score at age 11.5 years, −0.76) Setting: Ten US sites that participated in the National (adjusted relative risk = 2.63; 95% confidence interval, Institute of Child Health and Human Development Study 1.05-6.61; P = .04). of Early Child Care and Youth Development. Conclusions: The relationship between body fat and tim- Participants: Of 705 boys initially enrolled in the study, ing of pubertal onset is not the same in boys as it is in information about
JAMA Pediatrics – American Medical Association
Published: Feb 1, 2010
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