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Blood Pressure Changes After Adenotonsillectomy in Children With Obstructive Sleep Apnea—Reply

Blood Pressure Changes After Adenotonsillectomy in Children With Obstructive Sleep Apnea—Reply Letters Lindsay Reder, MD be mediated by increased sympathetic activity. Sympathetic Caitlin Bertelsen, MD activity surges during the obstructive episodes, mainly caused Karla O’Dell, MD by the synergistic influence of hypoxia and arousal resulting in a large surge in cardiovascular activity and an increase in Author Affiliations: Keck School of Medicine, Department of Otolaryngology– cardiac output and BP. Head & Neck Surgery, University of Southern California, Los Angeles, California. Furthermore, it has been shown that baroreflex sensitiv- Corresponding Author: Lindsay Reder, MD, Keck School of Medicine, ity decreased in children with moderate to severe OSA com- Department of Otolaryngology–Head & Neck Surgery, University of Southern pared with their healthy counterparts. Adenotonsillectomy California, 1540 Alcazar St, Suite 204M, Los Angeles, CA 90034 (lindsay.reder @med.usc.edu). leads to an increase in baroreflex sensitivity and a decrease in Published Online: April 26, 2018. doi:10.1001/jamaoto.2018.0317 BP variability during wakefulness and sleep. This effect may Conflict of Interest Disclosures: All authors have completed and submitted the be predicted by the change in the apnea-hypopnea and arousal ICMJE Form for Disclosure of Potential Conflicts of Interest and none were indices. reported. Importantly, Lee and colleagues found that nonhyperten- 1. Bertelsen C, Shoffel-Havakuk H, O’Dell K, Johns http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Otolaryngology - Head & Neck Surgery American Medical Association

Blood Pressure Changes After Adenotonsillectomy in Children With Obstructive Sleep Apnea—Reply

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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
2168-6181
eISSN
2168-619X
DOI
10.1001/jamaoto.2018.0454
Publisher site
See Article on Publisher Site

Abstract

Letters Lindsay Reder, MD be mediated by increased sympathetic activity. Sympathetic Caitlin Bertelsen, MD activity surges during the obstructive episodes, mainly caused Karla O’Dell, MD by the synergistic influence of hypoxia and arousal resulting in a large surge in cardiovascular activity and an increase in Author Affiliations: Keck School of Medicine, Department of Otolaryngology– cardiac output and BP. Head & Neck Surgery, University of Southern California, Los Angeles, California. Furthermore, it has been shown that baroreflex sensitiv- Corresponding Author: Lindsay Reder, MD, Keck School of Medicine, ity decreased in children with moderate to severe OSA com- Department of Otolaryngology–Head & Neck Surgery, University of Southern pared with their healthy counterparts. Adenotonsillectomy California, 1540 Alcazar St, Suite 204M, Los Angeles, CA 90034 (lindsay.reder @med.usc.edu). leads to an increase in baroreflex sensitivity and a decrease in Published Online: April 26, 2018. doi:10.1001/jamaoto.2018.0317 BP variability during wakefulness and sleep. This effect may Conflict of Interest Disclosures: All authors have completed and submitted the be predicted by the change in the apnea-hypopnea and arousal ICMJE Form for Disclosure of Potential Conflicts of Interest and none were indices. reported. Importantly, Lee and colleagues found that nonhyperten- 1. Bertelsen C, Shoffel-Havakuk H, O’Dell K, Johns

Journal

JAMA Otolaryngology - Head & Neck SurgeryAmerican Medical Association

Published: Jul 3, 2018

References