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B. Graham, J. Wilson, M. Tsao, M. Baumann, Shirley Brown (1951)
Development of neonatal electrolyte homeostasis.Pediatrics, 8 1
O. Schales, S. Schales (1941)
A SIMPLE AND ACCURATE METHOD FOR THE DETERMINATION OF CHLORIDE IN BIOLOGICAL FLUIDSJournal of Biological Chemistry, 140
I. Kaiser (1953)
The hydrogen ion concentration of human fetal blood in utero at term.Science, 118 3053
F. Sunderman, F. Boerner (1950)
Normal Values in Clinical MedicineThe Indian Medical Gazette, 85
Marinis Tp, Muirhead Ee (1947)
Sodium and potassium determinations in health and disease.Journal of Laboratory and Clinical Medicine, 32
R. Haden, F. Neff (1924)
THE VOLUME INDEX AND COLOR INDEX OF THE RED BLOOD CORPUSCLES IN NEWBORN INFANTSJAMA Pediatrics, 28
J. Mitchell (1929)
RELATIONSHIP OF JAUNDICE AND WEIGHT TO BLOOD VALUES IN THE NEW-BORN INFANTJAMA Pediatrics, 38
WITH THE development of ultramicromethods of analysis, it is possible to obtain blood-chemistry studies on capillary blood. This enables more and frequent determinations to be performed on the infant, since the need for a venipuncture, which may be harmful and is relatively difficult to perform, is now obviated. As is true of adults, 70% of the weight of a child is water; however, 50% of this is present in the extracellular fluid as against 20% for that of the adult. Therefore, a child exchanges close to half of the fluid of his extracellular compartment per 24 hours. This will cause body water and electrolyte losses to occur more readily than in an adult. For this reason, frequent electrolyte determinations, including sodium, chloride, and bicarbonate levels, are important in the infant. Very few such studies have been performed on normal full-term newborn babies. Sunderman and Boerner1 list no such normal
American journal of diseases of children – American Medical Association
Published: May 1, 1954
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