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β-Blockade in Noncardiac Surgery

β-Blockade in Noncardiac Surgery ORIGINAL ARTICLE Outcome at All Levels of Cardiac Risk Haytham M. A. Kaafarani, MD; Prasad V. Atluri, MD; John Thornby, PhD; Kamal M. F. Itani, MD Hypothesis: We hypothesized that the relationship Results: Patients at all levels of cardiac risk who re- among -blocker use, heart rate control, and periopera- ceived -blockers had lower preoperative and intraop- tive cardiovascular outcome would be similar in pa- erative heart rates. The -blocker group had higher rates tients at all levels of cardiac risk. of 30-day myocardial infarction (2.94% vs 0.74%, P=.03) and 30-day mortality (2.52% vs 0.25%, P=.007) com- Design: Retrospective cohort study. pared with the control group. In the -blocker group, patients who died perioperatively had significantly higher Setting: Michael E. DeBakey Veterans Affairs Medical preoperative heart rate (86 vs 70 beats/min, P=.03). None Center, Houston, Texas. of the deaths occurred among the patients at high car- diac risk. Patients: Among all patients who underwent various noncardiac surgical procedures in 2000, those who re- Conclusion: Among patients at all levels of cardiac ceived perioperative -blockers were matched and risk undergoing noncardiac surgery, administration of compared with a control group from the same patient -blockers should achieve adequate heart rate control http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Surgery American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-6254
eISSN
2168-6262
DOI
10.1001/archsurg.143.10.940
pmid
18936371
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL ARTICLE Outcome at All Levels of Cardiac Risk Haytham M. A. Kaafarani, MD; Prasad V. Atluri, MD; John Thornby, PhD; Kamal M. F. Itani, MD Hypothesis: We hypothesized that the relationship Results: Patients at all levels of cardiac risk who re- among -blocker use, heart rate control, and periopera- ceived -blockers had lower preoperative and intraop- tive cardiovascular outcome would be similar in pa- erative heart rates. The -blocker group had higher rates tients at all levels of cardiac risk. of 30-day myocardial infarction (2.94% vs 0.74%, P=.03) and 30-day mortality (2.52% vs 0.25%, P=.007) com- Design: Retrospective cohort study. pared with the control group. In the -blocker group, patients who died perioperatively had significantly higher Setting: Michael E. DeBakey Veterans Affairs Medical preoperative heart rate (86 vs 70 beats/min, P=.03). None Center, Houston, Texas. of the deaths occurred among the patients at high car- diac risk. Patients: Among all patients who underwent various noncardiac surgical procedures in 2000, those who re- Conclusion: Among patients at all levels of cardiac ceived perioperative -blockers were matched and risk undergoing noncardiac surgery, administration of compared with a control group from the same patient -blockers should achieve adequate heart rate control

Journal

JAMA SurgeryAmerican Medical Association

Published: Oct 1, 2008

References