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BILATERAL HYPOPLASTIC CYSTIC KIDNEYS

BILATERAL HYPOPLASTIC CYSTIC KIDNEYS Functional insufficiency of the kidney in early infancy produces characteristic clinical findings. These are best seen in cases of congenital chronic nephritis.1 Children so affected show great developmental disturbances dating from early life, if not from birth. Associated with the developmental disturbance are stunting and backwardness in growth, difficulty in feeding, anemia and rachitis. More direct evidence of renal insufficiency is given by the excretion of a large volume of dilute urine with a low specific gravity. This urine contains a slight amount of albumin, and casts are present in small numbers. In those cases in which it has been determined, the phenolsulphonepththalein excretion is low. Death usually results from uremia. The pathologic picture in these cases is similar to, if not identical with, that seen in the chronic diffuse nephritis of adults. The clinical findings in such cases, however, are determined by the functional rather than by the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

BILATERAL HYPOPLASTIC CYSTIC KIDNEYS

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Publisher
American Medical Association
Copyright
Copyright © 1922 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1922.04120070004001
Publisher site
See Article on Publisher Site

Abstract

Functional insufficiency of the kidney in early infancy produces characteristic clinical findings. These are best seen in cases of congenital chronic nephritis.1 Children so affected show great developmental disturbances dating from early life, if not from birth. Associated with the developmental disturbance are stunting and backwardness in growth, difficulty in feeding, anemia and rachitis. More direct evidence of renal insufficiency is given by the excretion of a large volume of dilute urine with a low specific gravity. This urine contains a slight amount of albumin, and casts are present in small numbers. In those cases in which it has been determined, the phenolsulphonepththalein excretion is low. Death usually results from uremia. The pathologic picture in these cases is similar to, if not identical with, that seen in the chronic diffuse nephritis of adults. The clinical findings in such cases, however, are determined by the functional rather than by the

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Jul 1, 1922

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