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Bilateral Confluent Drusen

Bilateral Confluent Drusen Abstract In the first case of this paper, extensive bilateral confluent drusen * of the kind seen in Doyne's honeycombed choroiditis are found related to an old choroiditis. A second case with bilateral confluent drusen in choroidal involvement in chronic granulocytic leukemia is briefly described. The hyaline depositions in both cases are believed to be the result of old exudation. Duke-Elder1 gives an excellent summary of the basic situations in which drusen or colloid bodies of Bruch's membrane may be found in the human eye: "A degeneration of this type occurs in three sets of circumstances: 1) as a senile phenomenon (in normal eyes), 2) as a degenerative phenomenon in diseased eyes (vascular, inflammatory, neoplastic), and 3) as a transmissible primary degeneration in which case it constitutes a separate clinical entity." Ophthalmoscopically, drusen represent yellowish spots deep in the retina. They are usually round and may be surrounded by a small References 1. There is some confusion in the American literature about the term drusen. Drusen is a German word for clear crystallizations found in rocks. They are commonly confused with Drüsen, the German word for gland. 2. Duke-Elder, W. S.: Text-Book of Ophthalmology , Vol. 3 St. Louis, The C. V. Mosby Company, 1941, p. 2747. 3. Mueller, H.: Anatomische Beitraege zur Ophthalmologie , Arch. Ophthal. 2:1 ( (Pt. 2) ) 1855.Crossref 4. Alt, A.: Beitrage zur pathologischen Anatomie des menschlichen Auges , Arch. Ophthal. Otolaryng. 6:304, 1877. 5. Donders, F. C.: Beitrage zur pathologischen Anatomie des Auges , Arch. Ophthal. 1:106 ( (Pt. 2) ) 1855.Crossref 6. de Vincentiis, cited by Rones.10 7. Kerschbaumer, R.: Über Altersveränderungen der Uvea , Arch. Ophthal. 38:127 ( (Pt. 1) ) 1892.Crossref 8. Schieck, F.: Zur Genese der sogenannten Drusen der Glaslamelle , Ber. Deutsch Ophthal. Ges. 1903, p. 320. 9. Rudnew, cited by Rones.10 10. Coats, G.: The Structure of the Membrane of Bruch, and Its Relations to the Formation of Colloid Excrescences , Roy. Lond. Ophthal. Hosp. Rep. 16: 164, 1904-1905. 11. Rones, B.: Formation of Drusen of the Lamina Vitrea , Arch. Ophthal. 18:388, 1937.Crossref 12. Verhoeff, F. H., in discussion on Rones,10 p. 400. 13. Wolter, J. R.: Die Histogenese der Drusen im Pigmentepithel der Netzhaut des menschlichen Auges , Klin. Mbl. Augenheilk. 130:86, 1957. 14. Wolter, J. R.: Pathology of So-Called Senile Guttate Choroiditis, 18th Concilium Ophthalmologicum 1958, Belgium, p. 435. 15. Leber, T., in Graefe and Saemisch: Handbuch der gesamten Augenheilkunde , Ed. 2, Leipzig, W. Engelmann, 1916, Vol. 17, Chap. 10 A, p. 2017. 16. Hutchinson, J.: Symmetrical Central Chorio-Retinitis Occurring in Senile Persons , Roy. Lond. Ophthal. Hosp. Rep. 8:23, 1876. 17. Gifford, S. R., and Cushman, B.: Certain Retinopathies Due to Changes in the Lamina Vitrea , Arch. Ophthal. 23:60, 1940.Crossref 18. Nuel, J. P.: Oedème vésiculaire de la macula lutea , Arch. Ophthal. (Par.) 28:737, 1908. 19. Doyne, R. W.: Peculiar Condition of Choroiditis Occurring in Several Members of the Same Family , Trans. Ophthal. Soc. U.K. 19:71, 1899. 20. Doyne, R. W.: Further Notes on Family Choroiditis , Trans. Ophthal. Soc. U.K. 30:274, 1910. 21. Sorsby, A.: The Dystrophies of the Macula , Brit. J. Ophthal. 24:469, 1940.Crossref 22. Collins, E. T.: A Pathological Report upon a Case of Doyne's Choroiditis , Ophthalmoscope 11:537, 1913. 23. Collins, E. T.: Hereditary Ocular Degenerations , in Proceedings of the International Congress of Ophthalmology , Washington, D.C., 1922, p. 103. 24. Fuchs, A.: Diseases of the Fundus Oculi , Blakiston Company, Philadelphia and Toronto, 1949, p. 161. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

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Publisher
American Medical Association
Copyright
Copyright © 1962 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1962.00960030223013
Publisher site
See Article on Publisher Site

Abstract

Abstract In the first case of this paper, extensive bilateral confluent drusen * of the kind seen in Doyne's honeycombed choroiditis are found related to an old choroiditis. A second case with bilateral confluent drusen in choroidal involvement in chronic granulocytic leukemia is briefly described. The hyaline depositions in both cases are believed to be the result of old exudation. Duke-Elder1 gives an excellent summary of the basic situations in which drusen or colloid bodies of Bruch's membrane may be found in the human eye: "A degeneration of this type occurs in three sets of circumstances: 1) as a senile phenomenon (in normal eyes), 2) as a degenerative phenomenon in diseased eyes (vascular, inflammatory, neoplastic), and 3) as a transmissible primary degeneration in which case it constitutes a separate clinical entity." Ophthalmoscopically, drusen represent yellowish spots deep in the retina. They are usually round and may be surrounded by a small References 1. There is some confusion in the American literature about the term drusen. Drusen is a German word for clear crystallizations found in rocks. They are commonly confused with Drüsen, the German word for gland. 2. Duke-Elder, W. S.: Text-Book of Ophthalmology , Vol. 3 St. Louis, The C. V. Mosby Company, 1941, p. 2747. 3. Mueller, H.: Anatomische Beitraege zur Ophthalmologie , Arch. Ophthal. 2:1 ( (Pt. 2) ) 1855.Crossref 4. Alt, A.: Beitrage zur pathologischen Anatomie des menschlichen Auges , Arch. Ophthal. Otolaryng. 6:304, 1877. 5. Donders, F. C.: Beitrage zur pathologischen Anatomie des Auges , Arch. Ophthal. 1:106 ( (Pt. 2) ) 1855.Crossref 6. de Vincentiis, cited by Rones.10 7. Kerschbaumer, R.: Über Altersveränderungen der Uvea , Arch. Ophthal. 38:127 ( (Pt. 1) ) 1892.Crossref 8. Schieck, F.: Zur Genese der sogenannten Drusen der Glaslamelle , Ber. Deutsch Ophthal. Ges. 1903, p. 320. 9. Rudnew, cited by Rones.10 10. Coats, G.: The Structure of the Membrane of Bruch, and Its Relations to the Formation of Colloid Excrescences , Roy. Lond. Ophthal. Hosp. Rep. 16: 164, 1904-1905. 11. Rones, B.: Formation of Drusen of the Lamina Vitrea , Arch. Ophthal. 18:388, 1937.Crossref 12. Verhoeff, F. H., in discussion on Rones,10 p. 400. 13. Wolter, J. R.: Die Histogenese der Drusen im Pigmentepithel der Netzhaut des menschlichen Auges , Klin. Mbl. Augenheilk. 130:86, 1957. 14. Wolter, J. R.: Pathology of So-Called Senile Guttate Choroiditis, 18th Concilium Ophthalmologicum 1958, Belgium, p. 435. 15. Leber, T., in Graefe and Saemisch: Handbuch der gesamten Augenheilkunde , Ed. 2, Leipzig, W. Engelmann, 1916, Vol. 17, Chap. 10 A, p. 2017. 16. Hutchinson, J.: Symmetrical Central Chorio-Retinitis Occurring in Senile Persons , Roy. Lond. Ophthal. Hosp. Rep. 8:23, 1876. 17. Gifford, S. R., and Cushman, B.: Certain Retinopathies Due to Changes in the Lamina Vitrea , Arch. Ophthal. 23:60, 1940.Crossref 18. Nuel, J. P.: Oedème vésiculaire de la macula lutea , Arch. Ophthal. (Par.) 28:737, 1908. 19. Doyne, R. W.: Peculiar Condition of Choroiditis Occurring in Several Members of the Same Family , Trans. Ophthal. Soc. U.K. 19:71, 1899. 20. Doyne, R. W.: Further Notes on Family Choroiditis , Trans. Ophthal. Soc. U.K. 30:274, 1910. 21. Sorsby, A.: The Dystrophies of the Macula , Brit. J. Ophthal. 24:469, 1940.Crossref 22. Collins, E. T.: A Pathological Report upon a Case of Doyne's Choroiditis , Ophthalmoscope 11:537, 1913. 23. Collins, E. T.: Hereditary Ocular Degenerations , in Proceedings of the International Congress of Ophthalmology , Washington, D.C., 1922, p. 103. 24. Fuchs, A.: Diseases of the Fundus Oculi , Blakiston Company, Philadelphia and Toronto, 1949, p. 161.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Aug 1, 1962

References