Abstract TUMORS arising in the pigment epithelium layer of the iris are exceedingly rare, according to reports in the literature. I do not refer here to the clumps of pigment epithelium commonly seen at the pupillary margin or to those cases in which a pigment clump can be seen arising from the posterior layer of the iris as an incidental clinical finding. The latter type has been reported by Schmidt,1 Alt,2 Anargyros,3 and Stock.4 Cases similar to the one I am describing in this paper have been reported by Morax,5 by Asbury,6 and, very recently, by Funk.7 I have not been able to find any similar case reports in a thorough search of the literature or in any textbook, including Duke-Elder's8 and Reese's.9 However, Berliner10 stated: ... The term "melanoma" should be reserved for those structures in which a small hyperplasia of References 1. Schmidt, R.: Ein epithelialer Tumor der Iris , Arch. Augenh. 108:457-463, 1934. 2. Alt, A.: On a Benign Epithelial Growth of the Iris , Am. J. Ophth. 28:39-45, 1911. 3. Anargyros, E.: Melanom der Iris , Arch. Augenh. 46:62-66, 1903. 4. Stock, W.: Ein epithelialer Tumor der Iris, vom hintern Pigmentepithel ausgehend , Klin. Monatsbl. 43:503-511, 1905. 5. Morax, V.: Epithelial pigmente et sarcome de l'iris , Bull. Soc. opht., Paris , pp. 102-106, 1925. 6. Asbury, M. K.: Epithelial Tumors of the Iris , Am. J. Ophth. 27:1094-1104, 1944. 7. Funk, V. A.: Melanoma of the Iris , Delaware M. J. 23:59-62 ( (March) ) 1951. 8. Duke-Elder, S.: Text-Book of Ophthalmology , Vol. III, St. Louis, C. V. Mosby Company, 1941. 9. Reese, A. B.: Tumors of the Eye , New York, Paul B. Hoeber, Inc. (Medical Book Department of Harper & Brothers), 1951. 10. Berliner, M. L.: Biomicroscopy of the Eye; Slit Lamp Microscopy of the Living Eye , New York, Paul B. Hoeber, 1949, Vol. 2, p. 767. 11. Vogt, A.: Atlas of the Slit Lamp Microscopy of the Living Eye, Vol. 3: Iris, Vitreous Body , Conjunctiva, New York, Hafner Publishing Company, Inc., 1947. 12. Stow, M. N.: Hyperplasia of the Pigment Epithelium of the Retina Simulating a Neoplasm , Tr. Am. Acad. Ophth. 54:674-677, 1949.
A.M.A. Archives of Ophthalmology – American Medical Association
Published: Jul 1, 1952
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