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Benign Chronic Bullous Dermatosis of Childhood: Linear IgA and C3 Deposition on the Basement Membrane

Benign Chronic Bullous Dermatosis of Childhood: Linear IgA and C3 Deposition on the Basement... Abstract • Benign chronic bullous dermatosis of childhood (BCBDC) is characterized by predominantly monomorphous, large, tense bullae with a predilection for the lower part of the trunk, the pelvic region, and the lower extremities. Most patients have blisters for two to three years and experience spontaneous exacerbations and remissions. We report the first case known to us in which a linear band of IgA (but no IgG or IgM) and complement was found at the epidermal basal lamina as demonstrated by immunoflurorescence studies. (Arch Dermatol 112:837-838, 1976) References 1. Bean SF, Jordon RE: Chronic nonhereditary blistering disease in children . Arch Dermatol 110:941-944, 1974.Crossref 2. Jordon RE, Bean SF, Triftshauser CT, et al: Childhood bullous dermatitis herpetiformis: Negative immunofluorescent tests . Arch Dermatol 101:629-634, 1970.Crossref 3. Bean SF, Jordon RE, Winkelmann RK, et al: Chronic nonhereditary blistering disease in children: Immunofluorescent studies . Am J Dis Child 122:137-141, 1971.Crossref 4. Kim R, Winkelmann RK: Dermatitis herpetiformis in children: Relationship to bullous pemphigoid . Arch Dermatol 83:895-902, 1961.Crossref 5. Bean SF, Good RA, Windhorst DB: Bullous pemphigoid in an 11-year-old boy . Arch Dermatol 102:205-208, 1970.Crossref 6. Fincher DF, Dupree E, Bean SF: Bullous pemphigoid in childhood: Immunofluorescent studies . Arch Dermatol 103:88-90, 1971.Crossref 7. Esterly NB, Gotoff SP, Lolekhas, et al: Bullous pemphigoid and membranous glomerulonephropathy in a child . J Pediatr 83:466-470, 1973.Crossref 8. Jablonska S, Chlorzelski T, Beutner EH, et al: Juvenile dermatitis herpetiformis in the light of immunofluorescence studies . Br J Dermatol 85:307-313, 1971.Crossref 9. Faber WR, Van Joost TH: Juvenile pemphigoid . Br J Dermatol 89:519-522, 1973.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Benign Chronic Bullous Dermatosis of Childhood: Linear IgA and C3 Deposition on the Basement Membrane

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Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1976.01630300045009
Publisher site
See Article on Publisher Site

Abstract

Abstract • Benign chronic bullous dermatosis of childhood (BCBDC) is characterized by predominantly monomorphous, large, tense bullae with a predilection for the lower part of the trunk, the pelvic region, and the lower extremities. Most patients have blisters for two to three years and experience spontaneous exacerbations and remissions. We report the first case known to us in which a linear band of IgA (but no IgG or IgM) and complement was found at the epidermal basal lamina as demonstrated by immunoflurorescence studies. (Arch Dermatol 112:837-838, 1976) References 1. Bean SF, Jordon RE: Chronic nonhereditary blistering disease in children . Arch Dermatol 110:941-944, 1974.Crossref 2. Jordon RE, Bean SF, Triftshauser CT, et al: Childhood bullous dermatitis herpetiformis: Negative immunofluorescent tests . Arch Dermatol 101:629-634, 1970.Crossref 3. Bean SF, Jordon RE, Winkelmann RK, et al: Chronic nonhereditary blistering disease in children: Immunofluorescent studies . Am J Dis Child 122:137-141, 1971.Crossref 4. Kim R, Winkelmann RK: Dermatitis herpetiformis in children: Relationship to bullous pemphigoid . Arch Dermatol 83:895-902, 1961.Crossref 5. Bean SF, Good RA, Windhorst DB: Bullous pemphigoid in an 11-year-old boy . Arch Dermatol 102:205-208, 1970.Crossref 6. Fincher DF, Dupree E, Bean SF: Bullous pemphigoid in childhood: Immunofluorescent studies . Arch Dermatol 103:88-90, 1971.Crossref 7. Esterly NB, Gotoff SP, Lolekhas, et al: Bullous pemphigoid and membranous glomerulonephropathy in a child . J Pediatr 83:466-470, 1973.Crossref 8. Jablonska S, Chlorzelski T, Beutner EH, et al: Juvenile dermatitis herpetiformis in the light of immunofluorescence studies . Br J Dermatol 85:307-313, 1971.Crossref 9. Faber WR, Van Joost TH: Juvenile pemphigoid . Br J Dermatol 89:519-522, 1973.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Jun 1, 1976

References