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Abstract THE SEVERAL pathogenic leptospira produce in man a group of closely related diseases. These infections have received considerable attention in Europe for many years. In the United States, leptospirosis has been identified almost exclusively with that due to Leptospira icterohaemorrhagiae (leptospiral jaundice, Weil's disease). It is becoming more obvious that other leptospiral disease is present. Several dozen cases of infection with Leptospira canicola (canicola fever),1 several instances of infection with Leptospira pomona (swineherd's disease),2 and an outbreak of disease attributed to Leptospira autumnalis (pretibial fever, Fort Bragg fever, autumnal fever)3 have been noted in this country. In November, 1952, Spain and Howard4 reported the first case of leptospirosis due to Leptospira grippotyphosa (mud fever) in the United States. Their patient had an icteric febrile illness. We are reporting a patient with an anicteric course marked by a benign aseptic meningitis. This is the second instance, to our knowledge, of leptospirosis References 1. Haunz, E. A., and Cardy, J. D.: Canicola Fever: Report of Nine Cases in One Family, with Abstract of the World Literature , A. M. A. Arch. Int. Med. 89:978 ( (June) ) 1952.Crossref 2. Schaeffer, M.: Leptospiral Meningitis: Investigation of a Water-Borne Epidemic Due to L. Pomona , J. Clin. Invest. 30:670 ( (June) ) 1951. 3. Coffey, J. H.; Dravin, I., and Dine, W. C.: Swineherd's Disease (Aseptic Meningitis) Due to Leptospira Pomona , J. A. M. A. 147:949 ( (Nov. 3) ) 1951.Crossref 4. Beeson, P. B.; Hankey, D. D., and Cooper, C. F., Jr.: Leptospiral Iridocyclitis: Evidence of Human Infection with Leptospira Pomona in the United States , J. A. M. A. 145:229 ( (Jan. 27) ) 1951.Crossref 5. Gochenour, W. S., Jr., and others: Leptospiral Etiology of Fort Bragg Fever , Pub. Health Rep. 67:811 ( (Aug.) ) 1952.Crossref 6. Spain, R. S., and Howard, G. T.: Leptospirosis Due to Leptospira Grippotyphosa: First Report of Occurrence in United States , J. A. M. A. 150:1010 ( (Nov. 8) ) 1952.Crossref 7. Yager, R. H.: Personal communication to the author. 8. Wilson, G. S., and Miles, A. A.: in Topley, W. W. C., and Wilson, G. S.: Topley and Wilson's Principles of Bacteriology and Immunity , Ed. 3, Baltimore, Williams & Wilkins Company, 1946, pp. 1836-1837. 9. Buckland, F. E., and Stuart, R. D.: Mud Fever (Leptospirosis) in the British Army in France , Lancet 2:331 ( (Sept. 15) ) 1945.Crossref 10. Leptospirosis in Man and Animals. Editorial , J. A. M. A. 150:1406 ( (Dec. 6) ) 1952.Crossref 11. Davenport, L. R.: Swineherd's Disease, Weekly Report, Division of Preventive Medicine , Illinois Department of Public Health, Aug. 16, 1952. 12. Sacks, M. S.: The Problem of Leptospirosis , Ann. Int. Med. 33:481 ( (Aug.) ) 1950.Crossref 13. Beeson, P. B., and Hankey, D D.: Leptospiral Meningitis , A. M. A. Arch. Int. Med. 89:575 ( (April) ) 1952.Crossref 14. Schuman, L. M.: Personal communication to the author.
A.M.A. Archives of Internal Medicine – American Medical Association
Published: Oct 1, 1953
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