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Beclomethasone Dipropionate Use in Chronic Asthmatic Patients

Beclomethasone Dipropionate Use in Chronic Asthmatic Patients The clinical effectiveness of beclomethasone dipropionate (BDP) aerosol and adrenal function after withdrawal of oral corticosteroid therapy were evaluated in 32 severely steroid-dependent asthmatic patients. Twenty-four of 28 patients were able to discontinue oral glucocorticosteroid therapy, while four failed to do so. Ventilatory studies showed no substantial changes at the end of six months' BDP treatment. In 24 patients, adrenal insufficiency was present before BDP therapy was started. In 20 of those patients, the response to cosyntropin returned to normal two months after discontinuation of systemic steroid treatment and administration of BDP. (JAMA 236:1969-1971, 1976) http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Beclomethasone Dipropionate Use in Chronic Asthmatic Patients

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References (8)

Publisher
American Medical Association
Copyright
Copyright © 1976 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1976.03270180045020
Publisher site
See Article on Publisher Site

Abstract

The clinical effectiveness of beclomethasone dipropionate (BDP) aerosol and adrenal function after withdrawal of oral corticosteroid therapy were evaluated in 32 severely steroid-dependent asthmatic patients. Twenty-four of 28 patients were able to discontinue oral glucocorticosteroid therapy, while four failed to do so. Ventilatory studies showed no substantial changes at the end of six months' BDP treatment. In 24 patients, adrenal insufficiency was present before BDP therapy was started. In 20 of those patients, the response to cosyntropin returned to normal two months after discontinuation of systemic steroid treatment and administration of BDP. (JAMA 236:1969-1971, 1976)

Journal

JAMAAmerican Medical Association

Published: Oct 25, 1976

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