Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

BASOPHILIC AGGREGATION IN THE NEW-BORN

BASOPHILIC AGGREGATION IN THE NEW-BORN It has been known for a long time that a basic staining substance is present in certain erythrocytes. By appropriate staining methods, this can be demonstrated as basophilic stippling, polychromatophilia or reticulation of these cells. Polychromatophilia appears as a diffuse double staining of the red cells; stippling shows as small deep blue granules. The reticulation—demonstrated best by supravital stains, such as brilliant cresyl blue—appears as a delicate network in various forms. It is probable in the light of modern researches that polychromatophilia, basophilic stippling and reticulation are merely different manifestations of the same process. This deduction, first made by Hawes,1 was confirmed by Schilling-Torgau.2 It is now quite generally believed that these basophilic forms are young (or immature) erythrocytes. The grounds for this belief are thus summarized by Key.3 In the circulating blood of normal adult humans, no polychromatophilia or punctate basophilia and not over http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American journal of diseases of children American Medical Association

Loading next page...
 
/lp/american-medical-association/basophilic-aggregation-in-the-new-born-AAiJty6hMR
Publisher
American Medical Association
Copyright
Copyright © 1925 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0096-8994
eISSN
1538-3628
DOI
10.1001/archpedi.1925.01920180064006
Publisher site
See Article on Publisher Site

Abstract

It has been known for a long time that a basic staining substance is present in certain erythrocytes. By appropriate staining methods, this can be demonstrated as basophilic stippling, polychromatophilia or reticulation of these cells. Polychromatophilia appears as a diffuse double staining of the red cells; stippling shows as small deep blue granules. The reticulation—demonstrated best by supravital stains, such as brilliant cresyl blue—appears as a delicate network in various forms. It is probable in the light of modern researches that polychromatophilia, basophilic stippling and reticulation are merely different manifestations of the same process. This deduction, first made by Hawes,1 was confirmed by Schilling-Torgau.2 It is now quite generally believed that these basophilic forms are young (or immature) erythrocytes. The grounds for this belief are thus summarized by Key.3 In the circulating blood of normal adult humans, no polychromatophilia or punctate basophilia and not over

Journal

American journal of diseases of childrenAmerican Medical Association

Published: Dec 1, 1925

There are no references for this article.