REVIEW Bariatric Surgery for Weight Loss and Glycemic Control in Nonmorbidly Obese Adults With Diabetes A Systematic Review Melinda Maggard-Gibbons, MD, MSHS Importance Bariatric surgery is beneficial in persons with a body mass index (BMI) Margaret Maglione, MPP of 35 or greater with obesity-related comorbidities. There is interest in using these pro- cedures in persons with lower BMI and diabetes. Masha Livhits, MD Objective To assess the association between bariatric surgery vs nonsurgical treat- Brett Ewing, MS ments and weight loss and glycemic control among patients with diabetes or impaired Alicia Ruelaz Maher, MD glucose tolerance and BMI of 30 to 35. Jianhui Hu, PhD Evidence Review PubMed, EMBASE, and Cochrane Library databases were searched from January 1985 through September 2012. Of 1291 screened articles, we included Zhaoping Li, MD, PhD 32 surgical studies, 11 systematic reviews on nonsurgical treatments, and 11 large non- Paul G. Shekelle, MD, PhD surgical studies published after those reviews. Weight loss, metabolic outcomes, and adverse events were abstracted by 2 independent reviewers. ARIATRIC SURGERY IS OFTEN used to promote weight loss Findings Three randomized clinical trials (RCTs) (N=290; including 1 trial of 150 pa- tients with type 2 diabetes and mean BMI of
JAMA – American Medical Association
Published: Jun 5, 2013
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