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BACTERIOPHAGE THERAPY

BACTERIOPHAGE THERAPY The purpose of this report is (a) to present summaries and discussions of (1) the experimentally determined facts relating to the bacteriophage phenomenon, (2) the laboratory and clinical evidence for and against the therapeutic usefulness of bacteriophage and (3) the relation of so-called antivirus to materials containing bacteriophage, and (b) to serve as a basis for a survey of the status of some of the commercial preparations. As it is impossible to include in this article an abstract of the whole voluminous and contradictory literature on these subjects, we have summarized only the papers and reviews that have appeared to us to be the most significant. MODE OF ACTION AND NATURE OF BACTERIOPHAGE Transmissible lysis of bacteria was discovered independently by Twort1 in 1915 and by d'Herelle2 in 1917. As d'Herelle has stated that he noticed the effect of the lytic agent first in 1909 and as the http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

BACTERIOPHAGE THERAPY

EATON, MONROE D.; BAYNE-JONES, STANHOPE
JAMA , Volume 103 (23) – Dec 8, 1934
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Publisher
American Medical Association
Copyright
Copyright © 1934 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1934.72750490003007
Publisher site
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Abstract

The purpose of this report is (a) to present summaries and discussions of (1) the experimentally determined facts relating to the bacteriophage phenomenon, (2) the laboratory and clinical evidence for and against the therapeutic usefulness of bacteriophage and (3) the relation of so-called antivirus to materials containing bacteriophage, and (b) to serve as a basis for a survey of the status of some of the commercial preparations. As it is impossible to include in this article an abstract of the whole voluminous and contradictory literature on these subjects, we have summarized only the papers and reviews that have appeared to us to be the most significant. MODE OF ACTION AND NATURE OF BACTERIOPHAGE Transmissible lysis of bacteria was discovered independently by Twort1 in 1915 and by d'Herelle2 in 1917. As d'Herelle has stated that he noticed the effect of the lytic agent first in 1909 and as the

Journal

JAMA – American Medical Association

Published: Dec 8, 1934

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