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Attempts at Sensitization to Skin in Guinea Pigs

Attempts at Sensitization to Skin in Guinea Pigs Abstract Attempts were made to sensitize guinea pigs to autologous and homologous skin by means of intracutaneous injections of skin in adjuvant emulsion. The results of the complement fixation tests and skin tests and the clinical changes noted failed to indicate the development of sensitivity to skin in these guinea pigs. References 1. Rosenthal, S. A.; Baer, R. L.; and Hagel, B.: Failure to Sensitize to Autologous Skin , Proc Soc Exp Biol Med 97:279-281, 1958.Crossref 2. Wilhelmj, C. M.; Kierland, R. R.; and Owen, C. A., Jr.: Production of Hypersensitivity to Skin in Animals , Arch Derm 86:161-182, 1962.Crossref 3. Kent, J. F.; Bukantz, S. C.; and Rein, C. R.: Studies in Complement Fixation: 1. Spectrophotometric Titration of Complement; Construction of Graphs for Direct Determination of 50 Per Cent Hemolytic Unit , J Immunol 53:37-50, 1946. 4. Kent, S. J.: On Abbreviated Spectrophotometric Technic for Determining Optimal Concentration of Amboceptor , J Lab Clin Med 31:1270-1277, 1946. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Attempts at Sensitization to Skin in Guinea Pigs

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Publisher
American Medical Association
Copyright
Copyright © 1964 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1964.01600060086014
Publisher site
See Article on Publisher Site

Abstract

Abstract Attempts were made to sensitize guinea pigs to autologous and homologous skin by means of intracutaneous injections of skin in adjuvant emulsion. The results of the complement fixation tests and skin tests and the clinical changes noted failed to indicate the development of sensitivity to skin in these guinea pigs. References 1. Rosenthal, S. A.; Baer, R. L.; and Hagel, B.: Failure to Sensitize to Autologous Skin , Proc Soc Exp Biol Med 97:279-281, 1958.Crossref 2. Wilhelmj, C. M.; Kierland, R. R.; and Owen, C. A., Jr.: Production of Hypersensitivity to Skin in Animals , Arch Derm 86:161-182, 1962.Crossref 3. Kent, J. F.; Bukantz, S. C.; and Rein, C. R.: Studies in Complement Fixation: 1. Spectrophotometric Titration of Complement; Construction of Graphs for Direct Determination of 50 Per Cent Hemolytic Unit , J Immunol 53:37-50, 1946. 4. Kent, S. J.: On Abbreviated Spectrophotometric Technic for Determining Optimal Concentration of Amboceptor , J Lab Clin Med 31:1270-1277, 1946.

Journal

Archives of DermatologyAmerican Medical Association

Published: Dec 1, 1964

References