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Asymptomatic Enlargement of the Sella Turcica

Asymptomatic Enlargement of the Sella Turcica Abstract Forty-six patients with enlarged sella turcica and pneumographic evidence of an intrasellar mass were initially untreated. The courses were variable, and 50% did not require subsequent treatment. All patients with initial visual involvement developed progressive visual impairment. Of patients with clinical evidence of pituitary insufficiency, 66% developed visual field defects and required treatment. Only one patient, whose sole symptom was headache, was subsequently treated, and no asymptomatic patient developed subsequent symptoms and required treatment. Asymptomatic patients with an enlarged sella turcica should have an air study to exclude an "empty sella" syndrome or primary hypothyroidism. References 1. Merritt HH: A Textbook of Neurology , ed 4. Philadelphia, Lea & Febiger, 1973, p 218. 2. Russell DS, Rubenstein LJ: Pathology of Tumors of the Nervous System . London, Edward Arnold Ltd, 1971, p 233. 3. Sheline GE, Boldrey EB: Chromophobe adenomas of the pituitary . Am J Roentgenol 92:160-166, 1964. 4. Nieman EA, Landon J: Endocrine function in patients with untreated chromophobe adenoma . Q J Med 36:357-392, 1967. 5. Chang CH, Pool JL: Radiotherapy of pituitary chromophobe adenomas . Radiology 89:1005-1015, 1967.Crossref 6. Elkington SG, McKissock W: Pituitary adenoma: Combined surgical and radiotherapy treatment . Br Med J 1:263-267, 1967.Crossref 7. Sheline G: Untreated and recurrent chromophobe adenomas of the pituitary . Radiology 112:768-773, 1971. 8. Kraus JE: Neoplastic diseases of the human hypophysis . Arch Pathol 39:343-349, 1945. 9. Costello RT: Subclinical adenoma of the pituitary gland . Am J Pathol 12:191-207, 1936. 10. King AB: Neurological conditions occurring as complications of pregnancy . Arch Neurol Psychiatr 63:611-620, 1950.Crossref 11. Kahana L: Endocrine manifestations of intracranial extrasellar lesions . J Clin Endocrinol 22:304-322, 1962.Crossref 12. Lawrence AM, Wilber JF: The pituitary and primary hypothyroidism . Arch Intern Med 132:327-333, 1973.Crossref 13. Caplan RH, Dobben GD: Endocrine studies in patients with the empty sella syndrome . Arch Intern Med 123:611-619, 1969.Crossref 14. Neelon FA, Goree JA: The primary empty sella . Medicine 52:73-92, 1973.Crossref 15. Hodgson SF, Randall RV: Empty sella syndrome . Med Clin N Am 56:897-907, 1972. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology American Medical Association

Asymptomatic Enlargement of the Sella Turcica

Archives of Neurology , Volume 32 (7) – Jul 1, 1975

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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0003-9942
eISSN
1538-3687
DOI
10.1001/archneur.1975.00490490087011
Publisher site
See Article on Publisher Site

Abstract

Abstract Forty-six patients with enlarged sella turcica and pneumographic evidence of an intrasellar mass were initially untreated. The courses were variable, and 50% did not require subsequent treatment. All patients with initial visual involvement developed progressive visual impairment. Of patients with clinical evidence of pituitary insufficiency, 66% developed visual field defects and required treatment. Only one patient, whose sole symptom was headache, was subsequently treated, and no asymptomatic patient developed subsequent symptoms and required treatment. Asymptomatic patients with an enlarged sella turcica should have an air study to exclude an "empty sella" syndrome or primary hypothyroidism. References 1. Merritt HH: A Textbook of Neurology , ed 4. Philadelphia, Lea & Febiger, 1973, p 218. 2. Russell DS, Rubenstein LJ: Pathology of Tumors of the Nervous System . London, Edward Arnold Ltd, 1971, p 233. 3. Sheline GE, Boldrey EB: Chromophobe adenomas of the pituitary . Am J Roentgenol 92:160-166, 1964. 4. Nieman EA, Landon J: Endocrine function in patients with untreated chromophobe adenoma . Q J Med 36:357-392, 1967. 5. Chang CH, Pool JL: Radiotherapy of pituitary chromophobe adenomas . Radiology 89:1005-1015, 1967.Crossref 6. Elkington SG, McKissock W: Pituitary adenoma: Combined surgical and radiotherapy treatment . Br Med J 1:263-267, 1967.Crossref 7. Sheline G: Untreated and recurrent chromophobe adenomas of the pituitary . Radiology 112:768-773, 1971. 8. Kraus JE: Neoplastic diseases of the human hypophysis . Arch Pathol 39:343-349, 1945. 9. Costello RT: Subclinical adenoma of the pituitary gland . Am J Pathol 12:191-207, 1936. 10. King AB: Neurological conditions occurring as complications of pregnancy . Arch Neurol Psychiatr 63:611-620, 1950.Crossref 11. Kahana L: Endocrine manifestations of intracranial extrasellar lesions . J Clin Endocrinol 22:304-322, 1962.Crossref 12. Lawrence AM, Wilber JF: The pituitary and primary hypothyroidism . Arch Intern Med 132:327-333, 1973.Crossref 13. Caplan RH, Dobben GD: Endocrine studies in patients with the empty sella syndrome . Arch Intern Med 123:611-619, 1969.Crossref 14. Neelon FA, Goree JA: The primary empty sella . Medicine 52:73-92, 1973.Crossref 15. Hodgson SF, Randall RV: Empty sella syndrome . Med Clin N Am 56:897-907, 1972.

Journal

Archives of NeurologyAmerican Medical Association

Published: Jul 1, 1975

References