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Association of Visual Field, Cup-Disc Ratio, and Magnetic Resonance Imaging of Optic Chiasm

Association of Visual Field, Cup-Disc Ratio, and Magnetic Resonance Imaging of Optic Chiasm Abstract Objective: To assess the association of visual field, vertical cup-disc (VC/D) ratio, and vertical height of optic chiasm. Design: Case series. Setting: Outpatient eye clinic. Patients: Eighteen patients with low, normal, or elevated intraocular pressure, with or without visual field defects. Intervention: Measurement of visual field, VC/D ratio, and vertical height of optic chiasm. Main Outcome Measures: Association between VC/D ratio and visual field defects compared with association between vertical height of optic chiasm and visual field defects. Results: Visual field defects were graded as 0, 1 to 10, and 11 to 20 (from least to most severe). Group mean VC/D ratios were 0.47 (0), 0.55 (1-10), and 0.69 (11-20) for right eyes and 0.48(0), 0.57 (1-10), and 0.75 (11-20) for left eyes. The significance level for trend was P=.02 for right eyes and P=.006 for left eyes. Group mean chiasm heights were 3.5 (0), 2.9 (1-10), and 2.2 (11-20) mm for right eyes and 3.5 (0), 2.8 (1-10), and 2.2 (11-20) mm for left eyes. The significance level for trend was P<.001 for right eyes and P=.002 for left eyes. To assess the simultaneous effects of VC/D ratio and chiasm height on the visual field defects groups, we used ordinal logistic regression models. Models with both variables implied that chiasm height was a stronger predictor of visual field defects group than VC/D ratio (for right eyes, P=.04 [VC/D ratio], P=.001 [chiasm height]; for left eyes, P=.11 [VC/D ratio], P=.005 [chiasm height]). Conclusions: When chiasm and VC/D ratio were analyzed in the same model, chiasm height was a stronger predictor of visual field defects. In advanced visual field defects, the optic chiasm is atrophic. References 1. Damms T, Dannheim F. Sensitivity and specificity of optic disc parameters in chronic glaucoma . Invest Ophthalmol Vis Sci . 1993;34:2246-2250. 2. Montgomery DM, Craig JP. Optic disc interpretation in glaucoma: is confidence misplaced? Ophthalmol Physiol Opt . 1993;13:383-386.Crossref 3. Abrams LS, Scott IU, Spaeth GL, Quigley HA, Varma R. Agreement among optometrists, ophthalmologists, and residents in evaluating the optic disc for glaucoma . Ophthalmology . 1994;101:1662-1667.Crossref 4. lester M, Traverso CE, Rolando M, Calabria G, Zingirian M. Study of the correlation between average values of optic disc parameters and their measurement variability using stereovideographic digital analysis . Ophthalmologica . 1995;209:177-181.Crossref 5. Bartz-Schmidt KU, Sundtgen M, Widder RA, Wever J, Krieglstein GK. Limits of two-dimensional planimetry in the follow-up of glaucomatous optic discs . Graefs Arch Clin Exp Ophthalmol . 1995;233:284-290.Crossref 6. Nicolela MT, Drance SM. Various glaucomatous optic nerve appearances: clinical correlations . Ophthalmology . 1996;103:640-649.Crossref 7. The Advanced Glaucoma Intervention Study Investigators. Advanced Glaucoma Intervention Study, II: visual field test scoring and reliability . Ophthalmology . 1994;101:1445-1455.Crossref 8. Leske MC, Connell AMS, Schachat AP, Hyman L, the Barbados Eye Study Group. The Barbados Eye Study: prevalence of open angle glaucoma . Arch Ophthalmol . 1994;112:821-829.Crossref 9. Winer BJ, Brown DR, Michels KM. Statistical Principles in Experimental Design . 3rd ed. New York, NY: McGraw-Hill Book Co; 1991. 10. Dixon WJ, ed. BMDP Statistical Software Manual: To Accompany the 7.0 Software Release . Berkeley: University of California Press; 1992. 11. Agresti A. Categorical Data Analysis . New York, NY: John Wiley & Sons Inc; 1990. 12. Gass A, Barker GJ, MacManus D, et al. High resolution magnetic resonance imaging of the anterior visual pathway in patients with optic neuropathies using fast spin echo and phased array local coils . J Neurol Neurosurg Psychiatry . 1995;58:562-569.Crossref 13. Imamura Y, Mashima Y, Oshitari K, Oguchi Y, Momoshima S, Shiga H. Detection of dilated subarachnoid space around the optic nerve in patients with papilloedema using T2 weighted fast spin echo imaging . J Neurol Neurosurg Psychiatry . 1996;60:108-109.Crossref 14. Tanino T, Mashima Y, Harashima N, Oshitari K, Oguchi Y. T2-weighted fast-spin echo MRI in patients with normal tension glaucoma (NTG) . Invest Ophthalmol Vis Sci . 1996;37( (suppl) ):S28. 15. Brodsky MC, Glasier CM, Pollock SC, Angtuago EJ. Optic nerve hypoplasia: identification by magnetic resonance imaging . Arch Ophthalmol . 1990;108:1562-1567.Crossref 16. Parravano JG, Toledo A, Kucharczyk W. Dimensions of the optic nerves, chiasm and tracts: MR quantitative comparison between patients with optic atrophy and normals . J Comput Assist Tomogr . 1993;17:688-690.Crossref 17. Stroman GA, Stewart WC, Golnik KC, Cur JK, Olinger RE. Magnetic resonance imaging in patients with low-tension glaucoma . Arch Ophthalmol . 1995;113:168-172.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Association of Visual Field, Cup-Disc Ratio, and Magnetic Resonance Imaging of Optic Chiasm

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Publisher
American Medical Association
Copyright
Copyright © 1997 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1997.01100150731006
Publisher site
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Abstract

Abstract Objective: To assess the association of visual field, vertical cup-disc (VC/D) ratio, and vertical height of optic chiasm. Design: Case series. Setting: Outpatient eye clinic. Patients: Eighteen patients with low, normal, or elevated intraocular pressure, with or without visual field defects. Intervention: Measurement of visual field, VC/D ratio, and vertical height of optic chiasm. Main Outcome Measures: Association between VC/D ratio and visual field defects compared with association between vertical height of optic chiasm and visual field defects. Results: Visual field defects were graded as 0, 1 to 10, and 11 to 20 (from least to most severe). Group mean VC/D ratios were 0.47 (0), 0.55 (1-10), and 0.69 (11-20) for right eyes and 0.48(0), 0.57 (1-10), and 0.75 (11-20) for left eyes. The significance level for trend was P=.02 for right eyes and P=.006 for left eyes. Group mean chiasm heights were 3.5 (0), 2.9 (1-10), and 2.2 (11-20) mm for right eyes and 3.5 (0), 2.8 (1-10), and 2.2 (11-20) mm for left eyes. The significance level for trend was P<.001 for right eyes and P=.002 for left eyes. To assess the simultaneous effects of VC/D ratio and chiasm height on the visual field defects groups, we used ordinal logistic regression models. Models with both variables implied that chiasm height was a stronger predictor of visual field defects group than VC/D ratio (for right eyes, P=.04 [VC/D ratio], P=.001 [chiasm height]; for left eyes, P=.11 [VC/D ratio], P=.005 [chiasm height]). Conclusions: When chiasm and VC/D ratio were analyzed in the same model, chiasm height was a stronger predictor of visual field defects. In advanced visual field defects, the optic chiasm is atrophic. References 1. Damms T, Dannheim F. Sensitivity and specificity of optic disc parameters in chronic glaucoma . Invest Ophthalmol Vis Sci . 1993;34:2246-2250. 2. Montgomery DM, Craig JP. Optic disc interpretation in glaucoma: is confidence misplaced? Ophthalmol Physiol Opt . 1993;13:383-386.Crossref 3. Abrams LS, Scott IU, Spaeth GL, Quigley HA, Varma R. Agreement among optometrists, ophthalmologists, and residents in evaluating the optic disc for glaucoma . Ophthalmology . 1994;101:1662-1667.Crossref 4. lester M, Traverso CE, Rolando M, Calabria G, Zingirian M. Study of the correlation between average values of optic disc parameters and their measurement variability using stereovideographic digital analysis . Ophthalmologica . 1995;209:177-181.Crossref 5. Bartz-Schmidt KU, Sundtgen M, Widder RA, Wever J, Krieglstein GK. Limits of two-dimensional planimetry in the follow-up of glaucomatous optic discs . Graefs Arch Clin Exp Ophthalmol . 1995;233:284-290.Crossref 6. Nicolela MT, Drance SM. Various glaucomatous optic nerve appearances: clinical correlations . Ophthalmology . 1996;103:640-649.Crossref 7. The Advanced Glaucoma Intervention Study Investigators. Advanced Glaucoma Intervention Study, II: visual field test scoring and reliability . Ophthalmology . 1994;101:1445-1455.Crossref 8. Leske MC, Connell AMS, Schachat AP, Hyman L, the Barbados Eye Study Group. The Barbados Eye Study: prevalence of open angle glaucoma . Arch Ophthalmol . 1994;112:821-829.Crossref 9. Winer BJ, Brown DR, Michels KM. Statistical Principles in Experimental Design . 3rd ed. New York, NY: McGraw-Hill Book Co; 1991. 10. Dixon WJ, ed. BMDP Statistical Software Manual: To Accompany the 7.0 Software Release . Berkeley: University of California Press; 1992. 11. Agresti A. Categorical Data Analysis . New York, NY: John Wiley & Sons Inc; 1990. 12. Gass A, Barker GJ, MacManus D, et al. High resolution magnetic resonance imaging of the anterior visual pathway in patients with optic neuropathies using fast spin echo and phased array local coils . J Neurol Neurosurg Psychiatry . 1995;58:562-569.Crossref 13. Imamura Y, Mashima Y, Oshitari K, Oguchi Y, Momoshima S, Shiga H. Detection of dilated subarachnoid space around the optic nerve in patients with papilloedema using T2 weighted fast spin echo imaging . J Neurol Neurosurg Psychiatry . 1996;60:108-109.Crossref 14. Tanino T, Mashima Y, Harashima N, Oshitari K, Oguchi Y. T2-weighted fast-spin echo MRI in patients with normal tension glaucoma (NTG) . Invest Ophthalmol Vis Sci . 1996;37( (suppl) ):S28. 15. Brodsky MC, Glasier CM, Pollock SC, Angtuago EJ. Optic nerve hypoplasia: identification by magnetic resonance imaging . Arch Ophthalmol . 1990;108:1562-1567.Crossref 16. Parravano JG, Toledo A, Kucharczyk W. Dimensions of the optic nerves, chiasm and tracts: MR quantitative comparison between patients with optic atrophy and normals . J Comput Assist Tomogr . 1993;17:688-690.Crossref 17. Stroman GA, Stewart WC, Golnik KC, Cur JK, Olinger RE. Magnetic resonance imaging in patients with low-tension glaucoma . Arch Ophthalmol . 1995;113:168-172.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jun 1, 1997

References