Abstract THE WORD nevus is derived from natus ("born") and was originally used loosely to designate almost any type of the so-called birthmark. It is still applied rather ambiguously to various unrelated conditions, principally to pigmented lesions of the skin and mucous membranes, but also commonly to certain types of hemangioma (naevus flammeus and port-wine hemangioma of the skin) and sometimes to various pigmented tumors of the uveal tract. It is now generally believed that the term should be restricted to lesions composed of so-called nevus cells. The nevus cell is a ubiquitous component, with definite characteristics ; but its precise nature has been the subject of extensive controversy. The argument has been raging, indeed, virtually from the birth of the cellular concept, and only in recent years have there been any areas of agreement among observers. At the present most pathologists accept the Masson theory that nevus cells are modified Schwann References 1. Wilder, H. C. : Intraocular Tumors in Soldiers, World War II , Mil. Surgeon , 99:459,1946. 2. A patient of Dr. John W. Burke. 3. Patient of Dr. Michael S. Brody. 4. A patient of Dr. Francis H. Adler and Dr. Irwin Levy. 5. A patient of Dr. Girolamo Bonaccolto. 6. Goldstein, I., and Wexler, D.: Melanosis Uveae and Melanoma of the Iris in Neurofibromatosis (Recklinghausen) , Arch. Ophth. 3:288 ( (March) ) 1930.Crossref 7. Bair, H. L., and Love, J. G.: Acoustic Neurofibroma Associated with Melano-Epithelioma of Choroid: Successful Removal of Both Tumors , Proc. Staff Meet., Mayo Clin. 12:481, 1937. 8. Gartner, S.: Malignant Melanoma of the Choroid and von Recklinghausen's Disease , Am. J. Ophth. 23:73, 1940. 9. Strakhov, V. P., and Shepkalova, V. M.: Recklinghausen's Disease, Neurinoma of the Right Orbit and Melanosarcoma of the Left Choroid , Vestnik oftal. 18:12, 1941. 10. Callender, G. R.; Wilder, H. C., and Ash, J. E.: Five Hundred Malignant Melanomas of Choroid and Ciliary Body Followed Five Years or Longer , Am. J. Ophth. 25:962, 1942.
A.M.A. Archives of Ophthalmology – American Medical Association
Published: Sep 1, 1952
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