Key PointsQuestionHow do nonfasting lipid levels compare with fasting lipid levels measured in the same individuals for assessing cardiovascular risk, and what is their association with incident cardiovascular events? FindingsIn this secondary analysis of 8270 participants in the Anglo-Scandinavian Cardiac Outcomes Trial–Lipid Lowering Arm, nonfasting lipid levels were similar to fasting lipid levels measured 4 weeks apart in the same participants in association with incident cardiovascular events overall and by randomized statin therapy. Concordance of fasting and nonfasting lipid levels for classifying participants into appropriate risk categories was high. MeaningThe present study provides robust evidence supportive of broader adoption of nonfasting lipid level measurement in clinical practice.
JAMA Internal Medicine – American Medical Association
Published: Jul 28, 2019
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