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Association of Intracerebral Hemorrhage Among Patients Taking Non–Vitamin K Antagonist vs Vitamin K Antagonist Oral Anticoagulants With In-Hospital Mortality

Association of Intracerebral Hemorrhage Among Patients Taking Non–Vitamin K Antagonist vs Vitamin... Key PointsQuestionWhat is the association between preceding oral anticoagulant use (warfarin, non–vitamin K oral anticoagulants [NOACs], and no oral anticoagulants) and in-hospital mortality among patients with intracerebral hemorrhage? FindingsIn this registry-based retrospective cohort study including 141 311 patients with intracerebral hemorrhage, prior use of warfarin or NOACs, compared with no prior anticoagulant use, was associated with higher in-hospital mortality, although the use of NOACs, compared with warfarin, was associated with lower in-hospital mortality risk (adjusted risk difference, −5.7%; adjusted odds ratio, 0.75). MeaningAmong patients with intracerebral hemorrhage, prior use of NOACs, compared with prior use of warfarin, was associated with lower risk of in-hospital mortality. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Association of Intracerebral Hemorrhage Among Patients Taking Non–Vitamin K Antagonist vs Vitamin K Antagonist Oral Anticoagulants With In-Hospital Mortality

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References (38)

Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2017.21917
pmid
29372247
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionWhat is the association between preceding oral anticoagulant use (warfarin, non–vitamin K oral anticoagulants [NOACs], and no oral anticoagulants) and in-hospital mortality among patients with intracerebral hemorrhage? FindingsIn this registry-based retrospective cohort study including 141 311 patients with intracerebral hemorrhage, prior use of warfarin or NOACs, compared with no prior anticoagulant use, was associated with higher in-hospital mortality, although the use of NOACs, compared with warfarin, was associated with lower in-hospital mortality risk (adjusted risk difference, −5.7%; adjusted odds ratio, 0.75). MeaningAmong patients with intracerebral hemorrhage, prior use of NOACs, compared with prior use of warfarin, was associated with lower risk of in-hospital mortality.

Journal

JAMAAmerican Medical Association

Published: Feb 6, 2018

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