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Key PointsQuestionWhat is the association between preceding oral anticoagulant use (warfarin, non–vitamin K oral anticoagulants [NOACs], and no oral anticoagulants) and in-hospital mortality among patients with intracerebral hemorrhage? FindingsIn this registry-based retrospective cohort study including 141 311 patients with intracerebral hemorrhage, prior use of warfarin or NOACs, compared with no prior anticoagulant use, was associated with higher in-hospital mortality, although the use of NOACs, compared with warfarin, was associated with lower in-hospital mortality risk (adjusted risk difference, −5.7%; adjusted odds ratio, 0.75). MeaningAmong patients with intracerebral hemorrhage, prior use of NOACs, compared with prior use of warfarin, was associated with lower risk of in-hospital mortality.
JAMA – American Medical Association
Published: Feb 6, 2018
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