Key PointsQuestionDo FLG loss-of-function variants differ between African American and white children with atopic dermatitis? FindingsIn a registry cohort of 741 children with atopic dermatitis, FLG loss-of-function variants differed significantly by race, were associated with race, and overall differences were noted with respect to whether any variant was present as well as the frequency of individual variants. MeaningThese findings suggest that using FLG loss-of-function variants to diagnose atopic dermatitis or to estimate the clinical course may be very difficult because very common variants in one race may be absent or very rare in another.
JAMA Dermatology – American Medical Association
Published: Dec 1, 2019
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera