Key PointsQuestionAre outcomes improved for patients with primary aldosteronism who undergo adrenal venous sampling prior to adrenalectomy in the setting of a clearly visualized unilateral adenoma and a normal contralateral gland? FindingsIn this multi-institutional study of 125 patients, there was no difference in complete biochemical success (75.9% vs 81.3%) or complete clinical success (43.6% vs 42.2%) based on whether adrenal venous sampling was performed preoperatively, nor was there a significant difference in partial biochemical or clinical success. MeaningIn the appropriate clinical setting, adrenal venous sampling may not be required for preoperative confirmation of diagnosis of aldosterone-producing adenoma.
JAMA Surgery – American Medical Association
Published: Feb 4, 2021