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Association of Adrenal Venous Sampling With Outcomes in Primary Aldosteronism for Unilateral Adenomas

Association of Adrenal Venous Sampling With Outcomes in Primary Aldosteronism for Unilateral... Key PointsQuestionAre outcomes improved for patients with primary aldosteronism who undergo adrenal venous sampling prior to adrenalectomy in the setting of a clearly visualized unilateral adenoma and a normal contralateral gland? FindingsIn this multi-institutional study of 125 patients, there was no difference in complete biochemical success (75.9% vs 81.3%) or complete clinical success (43.6% vs 42.2%) based on whether adrenal venous sampling was performed preoperatively, nor was there a significant difference in partial biochemical or clinical success. MeaningIn the appropriate clinical setting, adrenal venous sampling may not be required for preoperative confirmation of diagnosis of aldosterone-producing adenoma. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Surgery American Medical Association

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Publisher
American Medical Association
Copyright
Copyright 2020 American Medical Association. All Rights Reserved.
ISSN
2168-6254
eISSN
2168-6262
DOI
10.1001/jamasurg.2020.5011
Publisher site
See Article on Publisher Site

Abstract

Key PointsQuestionAre outcomes improved for patients with primary aldosteronism who undergo adrenal venous sampling prior to adrenalectomy in the setting of a clearly visualized unilateral adenoma and a normal contralateral gland? FindingsIn this multi-institutional study of 125 patients, there was no difference in complete biochemical success (75.9% vs 81.3%) or complete clinical success (43.6% vs 42.2%) based on whether adrenal venous sampling was performed preoperatively, nor was there a significant difference in partial biochemical or clinical success. MeaningIn the appropriate clinical setting, adrenal venous sampling may not be required for preoperative confirmation of diagnosis of aldosterone-producing adenoma.

Journal

JAMA SurgeryAmerican Medical Association

Published: Feb 4, 2021

References