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Association Between Marijuana Exposure and Pulmonary Function Over 20 Years

Association Between Marijuana Exposure and Pulmonary Function Over 20 Years ORIGINAL CONTRIBUTION Scan for Author Video Interview Association Between Marijuana Exposure and Pulmonary Function Over 20 Years Mark J. Pletcher, MD, MPH Context Marijuana smoke contains many of the same constituents as tobacco smoke, but whether it has similar adverse effects on pulmonary function is unclear. Eric Vittinghoff, PhD Ravi Kalhan, MD, MS Objective To analyze associations between marijuana (both current and lifetime ex- posure) and pulmonary function. Joshua Richman, MD, PhD Design, Setting, and Participants The Coronary Artery Risk Development in Young Monika Safford, MD Adults (CARDIA) study, a longitudinal study collecting repeated measurements of pul- Stephen Sidney, MD, MPH monary function and smoking over 20 years (March 26, 1985-August 19, 2006) in a cohort of 5115 men and women in 4 US cities. Mixed linear modeling was used to Feng Lin, MS account for individual age-based trajectories of pulmonary function and other covar- Stefan Kertesz, MD iates including tobacco use, which was analyzed in parallel as a positive control. Life- time exposure to marijuana joints was expressed in joint-years, with 1 joint-year of XPOSURE TO TOBACCO SMOKE exposure equivalent to smoking 365 joints or filled pipe bowls. causes lung damage with clini- Main Outcome Measures Forced expiratory http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Association Between Marijuana Exposure and Pulmonary Function Over 20 Years

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Publisher
American Medical Association
Copyright
Copyright 2012 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2011.1961
pmid
22235088
Publisher site
See Article on Publisher Site

Abstract

ORIGINAL CONTRIBUTION Scan for Author Video Interview Association Between Marijuana Exposure and Pulmonary Function Over 20 Years Mark J. Pletcher, MD, MPH Context Marijuana smoke contains many of the same constituents as tobacco smoke, but whether it has similar adverse effects on pulmonary function is unclear. Eric Vittinghoff, PhD Ravi Kalhan, MD, MS Objective To analyze associations between marijuana (both current and lifetime ex- posure) and pulmonary function. Joshua Richman, MD, PhD Design, Setting, and Participants The Coronary Artery Risk Development in Young Monika Safford, MD Adults (CARDIA) study, a longitudinal study collecting repeated measurements of pul- Stephen Sidney, MD, MPH monary function and smoking over 20 years (March 26, 1985-August 19, 2006) in a cohort of 5115 men and women in 4 US cities. Mixed linear modeling was used to Feng Lin, MS account for individual age-based trajectories of pulmonary function and other covar- Stefan Kertesz, MD iates including tobacco use, which was analyzed in parallel as a positive control. Life- time exposure to marijuana joints was expressed in joint-years, with 1 joint-year of XPOSURE TO TOBACCO SMOKE exposure equivalent to smoking 365 joints or filled pipe bowls. causes lung damage with clini- Main Outcome Measures Forced expiratory

Journal

JAMAAmerican Medical Association

Published: Jan 11, 2012

References