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- Publisher
- American Medical Association
- Copyright
- Copyright 2020 American Medical Association. All Rights Reserved.
- ISSN
- 2168-6068
- eISSN
- 2168-6084
- DOI
- 10.1001/jamadermatol.2020.4097
- Publisher site
- See Article on Publisher Site
Abstract
Key PointsQuestionWhat are the incidence rate and risk factors for keratoacanthoma? FindingsIn this cohort study of 40 438 residents of Queensland, Australia, the person-based incidence rate for keratoacanthoma was 409 individuals per 100 000 person-years. Older age, male sex, UV radiation exposure–sensitive phenotypes, indications of high sun exposure (such as previous keratinocyte cancer excisions), smoking, and high alcohol use were independently associated with the development of keratoacanthoma. MeaningThis analysis is, to date, the first large prospective cohort study to quantify the incidence rate and risk factors for keratoacanthoma, many of which are shared with other keratinocyte cancers.
Journal
JAMA Dermatology – American Medical Association
Published: Dec 7, 2020