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Aspartame as a Cause of Allergic Reactions, Including Anaphylaxis

Aspartame as a Cause of Allergic Reactions, Including Anaphylaxis Abstract Kemp et al1 failed to mention products containcontain- aspartame (NutraSweet) in their review of anaphylaxis. I emphasize this issue for three reasons. First, over half the adult population currently consumes aspartame products. Second, allergic-type reactions of various types occurred in one fifth of the aspartame reactors in my series,2,3 currently numbering more than 830. They include severe edema of the lips, tongue, and throat; urticaria; other skin eruptions; extensive itching; the aggravation of respiratory allergies; and even swelling of the salivary glands. Comparable reactions have been reported to the Food and Drug Administration in its database of more than 7300 consumers who volunteered reactions to aspartame products.4 Third, a number of these patients had dual sensitivities to both aspartame and monosodium glutamate, at times manifest as convulsions and other life-threatening reactions.5 These reactions may be due to the aspartame molecule, its three components, or the approximate References 1. Kemp SF, Lockey RF, Wolf BL, Lieberman P. Anaphylaxis: a review of 266. cases . Arch Intern Med. 1995;155:1749-1754.Crossref 2. Roberts HJ. Aspartame (NutraSweet): Is It safe? Philadelphia, Pa: Charles Press; 1989. 3. Roberts HJ. Sweet'ner Dearest: Bittersweet Vignettes About Aspartame (NutraSweet). West Palm Beach, Fla: Sunshine Sentinel Press; 1992. 4. Health Hazard Evaluation Board. Summary of Adverse Reactions Attributed to Aspartame . Washington, DC: US Dept of Health and Human Services; (April 20) , 1995. 5. Roberts HJ. Testimony presented to the Federation of American Societies for Experimental Biology Open Meeting on Analysis of Adverse Reactions to Monosodium Glutamate; April 8, 1993; Bethesda, Md. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Internal Medicine American Medical Association

Aspartame as a Cause of Allergic Reactions, Including Anaphylaxis

Archives of Internal Medicine , Volume 156 (9) – May 13, 1996

Aspartame as a Cause of Allergic Reactions, Including Anaphylaxis

Abstract

Abstract Kemp et al1 failed to mention products containcontain- aspartame (NutraSweet) in their review of anaphylaxis. I emphasize this issue for three reasons. First, over half the adult population currently consumes aspartame products. Second, allergic-type reactions of various types occurred in one fifth of the aspartame reactors in my series,2,3 currently numbering more than 830. They include severe edema of the lips, tongue, and throat; urticaria; other skin eruptions; extensive itching;...
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Publisher
American Medical Association
Copyright
Copyright © 1996 American Medical Association. All Rights Reserved.
ISSN
0003-9926
eISSN
1538-3679
DOI
10.1001/archinte.1996.00440090139016
Publisher site
See Article on Publisher Site

Abstract

Abstract Kemp et al1 failed to mention products containcontain- aspartame (NutraSweet) in their review of anaphylaxis. I emphasize this issue for three reasons. First, over half the adult population currently consumes aspartame products. Second, allergic-type reactions of various types occurred in one fifth of the aspartame reactors in my series,2,3 currently numbering more than 830. They include severe edema of the lips, tongue, and throat; urticaria; other skin eruptions; extensive itching; the aggravation of respiratory allergies; and even swelling of the salivary glands. Comparable reactions have been reported to the Food and Drug Administration in its database of more than 7300 consumers who volunteered reactions to aspartame products.4 Third, a number of these patients had dual sensitivities to both aspartame and monosodium glutamate, at times manifest as convulsions and other life-threatening reactions.5 These reactions may be due to the aspartame molecule, its three components, or the approximate References 1. Kemp SF, Lockey RF, Wolf BL, Lieberman P. Anaphylaxis: a review of 266. cases . Arch Intern Med. 1995;155:1749-1754.Crossref 2. Roberts HJ. Aspartame (NutraSweet): Is It safe? Philadelphia, Pa: Charles Press; 1989. 3. Roberts HJ. Sweet'ner Dearest: Bittersweet Vignettes About Aspartame (NutraSweet). West Palm Beach, Fla: Sunshine Sentinel Press; 1992. 4. Health Hazard Evaluation Board. Summary of Adverse Reactions Attributed to Aspartame . Washington, DC: US Dept of Health and Human Services; (April 20) , 1995. 5. Roberts HJ. Testimony presented to the Federation of American Societies for Experimental Biology Open Meeting on Analysis of Adverse Reactions to Monosodium Glutamate; April 8, 1993; Bethesda, Md.

Journal

Archives of Internal MedicineAmerican Medical Association

Published: May 13, 1996

References

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