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Arteriovenous Perfusion With the Disc Oxygenator: Treatment of Acute Respiratory Failure

Arteriovenous Perfusion With the Disc Oxygenator: Treatment of Acute Respiratory Failure Abstract ALTHOUGH commonly used in cardiac surgery, the artificial oxygenator has only rarely been employed in the support of the failing respiratory system. Furthermore the majority of these attempts were performed by means of a partial venoarterial1 or venovenous bypass2,3 which consequently necessitates the use of one or more pumps and thus complicates the technique and increases the trauma to the blood. Recently Rashkind et al4 evaluated a small bubble oxygenator of their construction and used an arteriovenous type of bypass. They postulated this method for the treatment of infants and newborns suffering from the respiratory distress syndrome. From these experiments, they concluded that the cardiac output and cardiac work during these perfusions was not increased over that of hypoxic puppies.5 The purpose of the following investigation was twofold: first, to determine the capability of the disc oxygenator when used as an arteriovenous bypass in sustaining the References 1. Lefemine, A.A.; Fosberg, A.M.; and Harken, D.E.: Prolonged Partial Extracorporeal Perfusion , Amer Heart J 75:531-536 ( (April) ) 1968.Crossref 2. Krasna, I.H., et al: Studies in Prolonged Veno-Venous Perfusion With Oxygenation in Hypoxia of Respiratory Origin , J Thorac Cardiovasc Surg 43:135-138 ( (Jan) ) 1962. 3. Schramel, R., et al: Treatment of Respiratory Insufficiency by Prolonged Extracorporeal Circulation , J Thorac Cardiovasc Surg 42:804-813 ( (Dec) ) 1961. 4. Rashkind, W.J., et al: Evaluation of a Disposable Plastic, Low Volume, Pumpless Oxygenator as a Lung Substitute , J Pediat 66:94-102 ( (Jan) ) 1965.Crossref 5. Rashkind, W.J., et al: Hemodynamic Effects of Arteriovenous Oxygenation With a Small Volume Artificial Extracorporeal Lung , J Pediat 70:425-429 ( (March) ) 1967.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

Arteriovenous Perfusion With the Disc Oxygenator: Treatment of Acute Respiratory Failure

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Publisher
American Medical Association
Copyright
Copyright © 1969 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1969.01340130071013
Publisher site
See Article on Publisher Site

Abstract

Abstract ALTHOUGH commonly used in cardiac surgery, the artificial oxygenator has only rarely been employed in the support of the failing respiratory system. Furthermore the majority of these attempts were performed by means of a partial venoarterial1 or venovenous bypass2,3 which consequently necessitates the use of one or more pumps and thus complicates the technique and increases the trauma to the blood. Recently Rashkind et al4 evaluated a small bubble oxygenator of their construction and used an arteriovenous type of bypass. They postulated this method for the treatment of infants and newborns suffering from the respiratory distress syndrome. From these experiments, they concluded that the cardiac output and cardiac work during these perfusions was not increased over that of hypoxic puppies.5 The purpose of the following investigation was twofold: first, to determine the capability of the disc oxygenator when used as an arteriovenous bypass in sustaining the References 1. Lefemine, A.A.; Fosberg, A.M.; and Harken, D.E.: Prolonged Partial Extracorporeal Perfusion , Amer Heart J 75:531-536 ( (April) ) 1968.Crossref 2. Krasna, I.H., et al: Studies in Prolonged Veno-Venous Perfusion With Oxygenation in Hypoxia of Respiratory Origin , J Thorac Cardiovasc Surg 43:135-138 ( (Jan) ) 1962. 3. Schramel, R., et al: Treatment of Respiratory Insufficiency by Prolonged Extracorporeal Circulation , J Thorac Cardiovasc Surg 42:804-813 ( (Dec) ) 1961. 4. Rashkind, W.J., et al: Evaluation of a Disposable Plastic, Low Volume, Pumpless Oxygenator as a Lung Substitute , J Pediat 66:94-102 ( (Jan) ) 1965.Crossref 5. Rashkind, W.J., et al: Hemodynamic Effects of Arteriovenous Oxygenation With a Small Volume Artificial Extracorporeal Lung , J Pediat 70:425-429 ( (March) ) 1967.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Jul 1, 1969

References