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ARSPHENAMIN ERUPTIONS RESEMBLING LICHEN PLANUS: A NEW CONCEPTION OF THE NATURE OF LICHEN PLANUS AS A CONSTITUTIONAL DISORDER

ARSPHENAMIN ERUPTIONS RESEMBLING LICHEN PLANUS: A NEW CONCEPTION OF THE NATURE OF LICHEN PLANUS... Abstract Two years ago, Buschke and Freymann1 separated from the large number of arsphenamin eruptions a certain group the symptomatology of which seemed to justify a special classification. Other authors shortly afterward reported numerous cases which were based on the same or similar observations. In each of these a lichen planus-like eruption had developed during or after a "course" of arsphenamin treatment, generally on the skin, occasionally on the mucosa. Histologically the picture was not in all cases typical of lichen planus. During the course of treatment in these cases the clinical disturbances occasionally disappeared, although as a rule they remained refractory and frequently became worse if arsphenamin medication was continued. All reporters agree that a lichen planus-like exanthem was provoked by arsphenamin, or that a histologically and clinically genuine lichen planus developed as a response to the administration of arsphenamin. We still lack a satisfactory explanation of the cause References 1. Buschke, A., and Freymann, W.: Arsphenamin Eruptions , Med. Klin. 7:899 ( (July 24) ) 1921. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology and Syphilology American Medical Association

ARSPHENAMIN ERUPTIONS RESEMBLING LICHEN PLANUS: A NEW CONCEPTION OF THE NATURE OF LICHEN PLANUS AS A CONSTITUTIONAL DISORDER

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Publisher
American Medical Association
Copyright
Copyright © 1924 American Medical Association. All Rights Reserved.
ISSN
0096-6029
DOI
10.1001/archderm.1924.02360220059006
Publisher site
See Article on Publisher Site

Abstract

Abstract Two years ago, Buschke and Freymann1 separated from the large number of arsphenamin eruptions a certain group the symptomatology of which seemed to justify a special classification. Other authors shortly afterward reported numerous cases which were based on the same or similar observations. In each of these a lichen planus-like eruption had developed during or after a "course" of arsphenamin treatment, generally on the skin, occasionally on the mucosa. Histologically the picture was not in all cases typical of lichen planus. During the course of treatment in these cases the clinical disturbances occasionally disappeared, although as a rule they remained refractory and frequently became worse if arsphenamin medication was continued. All reporters agree that a lichen planus-like exanthem was provoked by arsphenamin, or that a histologically and clinically genuine lichen planus developed as a response to the administration of arsphenamin. We still lack a satisfactory explanation of the cause References 1. Buschke, A., and Freymann, W.: Arsphenamin Eruptions , Med. Klin. 7:899 ( (July 24) ) 1921.

Journal

Archives of Dermatology and SyphilologyAmerican Medical Association

Published: Apr 1, 1924

References

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