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Are We Making Any Progress?

Are We Making Any Progress? Abstract The head and neck oncologists seem to be facing a complication with their success. As specialists in the field, we have increased the effectiveness of treatment as well as reached a laudable figure of 85% to 90% of patients who are rendered free of cancer above the clavicle. We must now conquer at a different front. The biology of the tumor, its interaction with the host, and the still unresolved secrets of carcinogenesis need to be addressed and solved. These facts are not new. See also p 564. In this issue of the Archives, Vikram1 demonstrates again that combined surgery and postoperative irradiation yield a better regional and local tumor eradication than surgery applied by itself. The point is proved through the comparison of present therapy results with those achieved in historic controls. Purists may argue that many changes took place during the last 20 years covered by this References 1. Vikram B: Changing patterns of failure in advanced head and neck cancer . Arch Otolaryngol 1984;110:564-565.Crossref 2. Fletcher GH, Jesse RH: Interaction of surgery and irradiation in head and neck cancers . Current Problems in Radiology. Chicago, New York Medical Publishers, 1971. 3. Merino OR, Lindberg RD, Fletcher GH: An analysis of distant metastases from squamous cell carcinoma of the upper respiratory and digestive tracts . Cancer 1977;40:145-151.Crossref 4. El Badawi SA, Goepfert H, Fletcher GH, et al: Squamous cell carcinoma of the pyriform sinus . Laryngoscope 1982;92:357-364. 5. Johnson JT, Barnes EL, Myers EN, et al: The extracapsular spread of tumors in cervical node metastasis . Arch Otolaryngol 1981;107:725-729.Crossref 6. Vikram B: Importance of the time interval between surgery and postoperative radiation therapy in the combined management of head and neck cancer . Int J Radiat Oncol Biol Phys 1979;5:1837-1840.Crossref 7. Lindberg RD: Sites of failure in head and neck cancer . Cancer Treat Symp 1983;2:21-31. 8. Marcial VA, Amato DA, Pajok TF: Patterns of failure after treatment for cancer of upper respiratory and digestive tracts: A radiation therapy oncology group report . Cancer Treat Symp 1983;2:33-40. 9. Jesse RH, Sugarbaker EV: Squamous cell carcinoma of the oropharynx: Why we fail . Am J Surg 1976;132:435-458.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

Are We Making Any Progress?

GOEPFERT, HELMUTH
Archives of Otolaryngology , Volume 110 (9) – Sep 1, 1984
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Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1984.00800350004002
Publisher site
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Abstract

Abstract The head and neck oncologists seem to be facing a complication with their success. As specialists in the field, we have increased the effectiveness of treatment as well as reached a laudable figure of 85% to 90% of patients who are rendered free of cancer above the clavicle. We must now conquer at a different front. The biology of the tumor, its interaction with the host, and the still unresolved secrets of carcinogenesis need to be addressed and solved. These facts are not new. See also p 564. In this issue of the Archives, Vikram1 demonstrates again that combined surgery and postoperative irradiation yield a better regional and local tumor eradication than surgery applied by itself. The point is proved through the comparison of present therapy results with those achieved in historic controls. Purists may argue that many changes took place during the last 20 years covered by this References 1. Vikram B: Changing patterns of failure in advanced head and neck cancer . Arch Otolaryngol 1984;110:564-565.Crossref 2. Fletcher GH, Jesse RH: Interaction of surgery and irradiation in head and neck cancers . Current Problems in Radiology. Chicago, New York Medical Publishers, 1971. 3. Merino OR, Lindberg RD, Fletcher GH: An analysis of distant metastases from squamous cell carcinoma of the upper respiratory and digestive tracts . Cancer 1977;40:145-151.Crossref 4. El Badawi SA, Goepfert H, Fletcher GH, et al: Squamous cell carcinoma of the pyriform sinus . Laryngoscope 1982;92:357-364. 5. Johnson JT, Barnes EL, Myers EN, et al: The extracapsular spread of tumors in cervical node metastasis . Arch Otolaryngol 1981;107:725-729.Crossref 6. Vikram B: Importance of the time interval between surgery and postoperative radiation therapy in the combined management of head and neck cancer . Int J Radiat Oncol Biol Phys 1979;5:1837-1840.Crossref 7. Lindberg RD: Sites of failure in head and neck cancer . Cancer Treat Symp 1983;2:21-31. 8. Marcial VA, Amato DA, Pajok TF: Patterns of failure after treatment for cancer of upper respiratory and digestive tracts: A radiation therapy oncology group report . Cancer Treat Symp 1983;2:33-40. 9. Jesse RH, Sugarbaker EV: Squamous cell carcinoma of the oropharynx: Why we fail . Am J Surg 1976;132:435-458.Crossref

Journal

Archives of Otolaryngology – American Medical Association

Published: Sep 1, 1984

References

  • Changing patterns of failure in advanced head and neck cancer
    Vikram B
  • Interaction of surgery and irradiation in head and neck cancers
    Fletcher GH, Jesse RH
  • An analysis of distant metastases from squamous cell carcinoma of the upper respiratory and digestive tracts
    Merino OR, Lindberg RD, Fletcher GH
  • Squamous cell carcinoma of the pyriform sinus
    El Badawi SA, Goepfert H, Fletcher GH, et al
  • The extracapsular spread of tumors in cervical node metastasis
    Johnson JT, Barnes EL, Myers EN, et al
  • Importance of the time interval between surgery and postoperative radiation therapy in the combined management of head and neck cancer
    Vikram B
  • Sites of failure in head and neck cancer
    Lindberg RD
  • Patterns of failure after treatment for cancer of upper respiratory and digestive tracts: A radiation therapy oncology group report
    Marcial VA, Amato DA, Pajok TF
  • Squamous cell carcinoma of the oropharynx: Why we fail
    Jesse RH, Sugarbaker EV