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APACHE II Scores in the Prediction of Multiple Organ Failure Syndrome

APACHE II Scores in the Prediction of Multiple Organ Failure Syndrome Abstract To the Editor.—The recent paper by Cerra et al1 presents the results of a clinical study using the APACHE II (acute physiology and chronic health evaluation) score to predict the development of and mortality associated with multiple organ failure syndrome. The authors conclude that the APACHE II score is an insensitive predictor of this disease. We would like to highlight several shortcomings in this study's methods. The APACHE II risk prediction equation was designed to stratify the risk of unselected patients in 13 US medical and surgical intensive care units. In the retrospective study by Cerra et al, significantly different and more stringent selection criteria were used. Eligible patients all experienced precipitating events such as septic shock and subsequent surgical interventions within 24 hours of admission to the intensive care unit. In addition, eligible patients had to develop pulmonary failure, require mechanical ventilation, References 1. Cerra FB, Negro F, Abrams J. APACHE II score does not predict multiple organ failure or mortality in postoperative surgical patients . Arch Surg . 1990;125:519-522.Crossref 2. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system . Crit Care Med . 1985;13:818-829.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Surgery American Medical Association

APACHE II Scores in the Prediction of Multiple Organ Failure Syndrome

APACHE II Scores in the Prediction of Multiple Organ Failure Syndrome

Abstract

Abstract To the Editor.—The recent paper by Cerra et al1 presents the results of a clinical study using the APACHE II (acute physiology and chronic health evaluation) score to predict the development of and mortality associated with multiple organ failure syndrome. The authors conclude that the APACHE II score is an insensitive predictor of this disease. We would like to highlight several shortcomings in this study's methods. The APACHE II risk prediction equation was designed to...
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Publisher
American Medical Association
Copyright
Copyright © 1991 American Medical Association. All Rights Reserved.
ISSN
0004-0010
eISSN
1538-3644
DOI
10.1001/archsurg.1991.01410280132022
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.—The recent paper by Cerra et al1 presents the results of a clinical study using the APACHE II (acute physiology and chronic health evaluation) score to predict the development of and mortality associated with multiple organ failure syndrome. The authors conclude that the APACHE II score is an insensitive predictor of this disease. We would like to highlight several shortcomings in this study's methods. The APACHE II risk prediction equation was designed to stratify the risk of unselected patients in 13 US medical and surgical intensive care units. In the retrospective study by Cerra et al, significantly different and more stringent selection criteria were used. Eligible patients all experienced precipitating events such as septic shock and subsequent surgical interventions within 24 hours of admission to the intensive care unit. In addition, eligible patients had to develop pulmonary failure, require mechanical ventilation, References 1. Cerra FB, Negro F, Abrams J. APACHE II score does not predict multiple organ failure or mortality in postoperative surgical patients . Arch Surg . 1990;125:519-522.Crossref 2. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system . Crit Care Med . 1985;13:818-829.Crossref

Journal

Archives of SurgeryAmerican Medical Association

Published: Apr 1, 1991

References