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Antiplatelet and Anticoagulant Therapy in Patients With Gastrointestinal Bleeding

Antiplatelet and Anticoagulant Therapy in Patients With Gastrointestinal Bleeding CLINICAL CROSSROADS CLINICIAN’S CORNER CONFERENCES WITH PATIENTS AND DOCTORS Antiplatelet and Anticoagulant Therapy in Patients With Gastrointestinal Bleeding An 86-Year-Old Woman With Peptic Ulcer Disease Majid A. Almadi, MBBS, FRCPC, MSc(Epi) Bleeding in the upper gastrointestinal tract is a common Alan Barkun, MDCM, FRCPC, MSc(Epi) medical problem, with an incidence of 48 to 160 cases per James Brophy, MEng, MD, FRCPC, PhD 1000 adults per year and a mortality rate of 5% to 14%. The risk of gastrointestinal bleeding is increased with the N 86-YEAR-OLD WOMAN,MS S, IS PHYSICALLY AC- tive, engages in numerous social activities, and at- use of antiplatelet medications including aspirin and clopi- tends a class in political science. She presented to dogrel, as well as warfarin or a combination of these medi- Athe emergency department after falling in her bath- cations. The recurrence rate for bleeding in patients who room. Ms S had been feeling epigastric discomfort that was continue to take aspirin after an episode of peptic ulcer dis- difficult to describe; it was episodic in nature and mild in ease–related bleeding can reach up to 300 cases per 1000 intensity and there were no provocative or palliative fac- person-years and varies by age, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Antiplatelet and Anticoagulant Therapy in Patients With Gastrointestinal Bleeding

JAMA , Volume 306 (21) – Dec 7, 2011

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Publisher
American Medical Association
Copyright
Copyright 2011 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2011.1653
pmid
22045703
Publisher site
See Article on Publisher Site

Abstract

CLINICAL CROSSROADS CLINICIAN’S CORNER CONFERENCES WITH PATIENTS AND DOCTORS Antiplatelet and Anticoagulant Therapy in Patients With Gastrointestinal Bleeding An 86-Year-Old Woman With Peptic Ulcer Disease Majid A. Almadi, MBBS, FRCPC, MSc(Epi) Bleeding in the upper gastrointestinal tract is a common Alan Barkun, MDCM, FRCPC, MSc(Epi) medical problem, with an incidence of 48 to 160 cases per James Brophy, MEng, MD, FRCPC, PhD 1000 adults per year and a mortality rate of 5% to 14%. The risk of gastrointestinal bleeding is increased with the N 86-YEAR-OLD WOMAN,MS S, IS PHYSICALLY AC- tive, engages in numerous social activities, and at- use of antiplatelet medications including aspirin and clopi- tends a class in political science. She presented to dogrel, as well as warfarin or a combination of these medi- Athe emergency department after falling in her bath- cations. The recurrence rate for bleeding in patients who room. Ms S had been feeling epigastric discomfort that was continue to take aspirin after an episode of peptic ulcer dis- difficult to describe; it was episodic in nature and mild in ease–related bleeding can reach up to 300 cases per 1000 intensity and there were no provocative or palliative fac- person-years and varies by age,

Journal

JAMAAmerican Medical Association

Published: Dec 7, 2011

References