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R. Berliner, D. Earle, J. Taggart, C. Zubrod, William Welch, N. Conan, E. Bauman, Sidney Scudder, J. Shannon (1948)
STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. VI. THE PHYSIOLOGICAL DISPOSITION, ANTIMALARIAL ACTIVITY, AND TOXICITY OF SEVERAL DERIVATIVES OF 4-AMINOQUINOLINE.The Journal of clinical investigation, 27 3 Pt 2
A. J. Prokoptchouk (1940)
Treatment of Lupus Erythematosus with AcriquineVestnik venerol. i dermat.
F. Herrmann (1952)
Pharmacologic and Pathogenic Effects of Mepacrine Hydrochloride (Atabrine®) on Human Skin. I. Clinical and Experimental ObservationsActa dermat.-venereol., 32
Herrmann (1952)
II. Microscopic Studies of Vital Staining Effects in SkinActa dermat.-venereol., 32
L. G. Parmer (1953)
Fatal Aplastic Anemia Following Quinacrine Therapy in Chronic Discoid Lupus ErythematosusJ. A. M. A., 153
B. Rhodes, M. Allende (1954)
Treatment of chronic discoid lupus erythematosus with quinacrine.California medicine, 80 2
Bkitish Jouenal (1953)
THE TREATMENT OF LUPUS ERYTHEMATOSUS WITH MEPACRINE AND PARA‐AMINOBENZOIC ACID.British Journal of Dermatology, 65
J. Sommerville, D. Devine, J. Logan (1952)
LUPUS ERYTHEMATOSUS TREATED WITH MEPACRINEBritish Journal of Dermatology, 64
D. Pillsbury, C. Jacobson (1954)
TREATMENT OF CHRONIC DISCOID LUPUS ERYTHEMATOSUS WITH CHLOROQUINE (ARALEN)JAMA, 154
E. M. Farber (1953)
Atabrine® and Chloroquine in the Treatment of Chronic Discoid Lupus Erythematosus: A Preliminary ReportStanford M. Bull., 11
M. Sulzberger, R. Baer (1951)
A YEAR BOOK OF DERMATOLOGY AND SYPHILOLOGYMedical Journal of Australia, 2
F. Page (1951)
Treatment of lupus erythematosus with mepacrine.Lancet, 2 6687
H. Sawicky, N. Kanof, M. Silverberg, M. Braitman, B. Kalish (1952)
Therapeutic assays of the Skin and Cancer Unit of the New York University Hospital. Assay VII-Quinacrine hydrochloride (atabrine hydrochloride) for chronic discoid lupus erythematosus.Journal of Investigative Dermatology, 19
L. Goldman , D. P. Cole (1953)
Chloroquine Diphosphate in the Treatment of Discoid Lupus ErythematosusJ. A. M. A., 152
J. Rogers, O. Finn (1954)
Synthetic antimalarial drugs in chronic discoid lupus erythematosus and light eruptions.A.M.A. archives of dermatology and syphilology, 70 1
H. Black (1953)
The Treatment of Lupus Erythematosus with Mepacrine and ParaaminobenzoicAcid. Brit. J. Dermat., 65
F. OTTOLENGHI-LODIGIANI (1955)
[Treatment of chronic lupus erythematosus, local intradermal infiltration with an acridine preparation].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 6 1
J. Cramer, G. Lewis (1952)
Atabrine in the treatment of discoid lupus erythematosus.The Journal of investigative dermatology, 19 6
J. C. Hathaway (1954)
Therapeutic Committee Evaluation Report: The Value of Atabrine Therapy in Chronic Discoid Lupus ErythematosusTr. Pacific Dermat. A. (6th Annual Meeting), 1
L. Popoff (1943)
Case PresentationsDermat. Wchnschr., 116
Harold Cole, Shaker Heights, Paul Chivington, James Driver (1953)
TREATMENT OF CHRONIC DISCOID LUPUS ERYTHEMATOSUS WITH QUINACRINEJAMA, 153
E. Dubois (1954)
Quinacrine (atabrine) in treatment of systemic and discoid lupus erythematosus.A.M.A. archives of internal medicine, 94 1
L. Parmer, A. Sawitsky (1953)
Fatal aplastic anemia following quinacrine therapy in chronic discoid lupus erythematosus.Journal of the American Medical Association, 153 13
F. G. Novy (1954)
Therapeutic Committee Evaluation Report: Chloroquine Therapy and Discoid Lupus ErythematosusTr. Pacific Dermat. A. (6th Annual Meeting), 1
G. Wells (1952)
Treatment of chronic discoid lupus erythematosus with atabrine.The Journal of investigative dermatology, 19 6
S. Zakon, Judd Gershenson (1955)
INTRODUCTION OF QUINACRINE IN TREATMENT OF LUPUS ERYTHEMATOSUSArchives of Dermatology, 71
L. Goldman, D. Cole, R. Preston (1953)
Chloroquine diphosphate in treatment of discoid lupus erythematosus.Journal of the American Medical Association, 152 15
E. L. Dubois (1954)
Quinacrine (Atabrine) in Treatment of Systemic and Discoid Lupus ErythematosusA. M. A. Arch. Int. Med., 94
Abstract In recent years the effective treatment of discoid lupus erythematosus has been greatly advanced by the introduction of antimalarial drugs. While this as well as former methods of treatment remain on a purely empirical basis, awaiting fuller understanding of the pathogenesis of lupus erythematosus, it is now evident that quinacrine (Atabrine) and chloroquine (Aralen) afford suppression or control of the disease more consistently than any of the older therapeutic agents. The interesting history of the employment of antimalarials for lupus erythematosus has been recounted in several recent contributions.* Chloroquine has found acceptance as being superior to quinacrine in avoiding the undesirable skin discoloration and hematologic risks of the latter. Attention now is centered upon the investigation of other antimalarial drugs in the effort to find those which are most beneficial and at the same time least toxic. The present report includes observations on the use of quinacrine, chloroquine, References 1. References 2 to 24. 2. The Camoquin was supplied through the courtesy of Dr. Eugene H. Payne of the Department of Clinical Investigation, Parke, Davis & Company, Detroit. 3. Berliner, R. W., and others: Studies on the Chemotherapy of the Human Malarias: VI. The Physiological Disposition, Antimalarial Activity and Toxicity of Several Derivatives of 4-Aminoquinoline , J. Clin. Invest. 27:98 (May, Part (2) ) 1948.Crossref 4. Black, H.: The Treatment of Lupus Erythematosus with Mepacrine and Paraaminobenzoic Acid. Brit. J. Dermat. 65:195-203 ( (June) ) 1953.Crossref 5. Cole, H. N., Jr.; Chivington, P. V., Jr.; Cole, H. N., and Driver, J. R., Jr.: Treatment of Chronic Discoid Lupus Erythematosus with Quinacrine , J. A. M. A. 153:1515-1516 ( (Dec. 26) ) 1953.Crossref 6. Cramer, J. A., and Lewis, G. M.: Atabrine in the Treatment of Discoid Lupus Erythematosus , J. Invest. Dermat. 19:393-395 ( (Dec.) ) 1952.Crossref 7. Dubois, E. L.: Quinacrine (Atabrine) in Treatment of Systemic and Discoid Lupus Erythematosus , A. M. A. Arch. Int. Med. 94:131-141 ( (July) ) 1954.Crossref 8. Farber, E. M., and Driver, I. E.: Atabrine® and Chloroquine in the Treatment of Chronic Discoid Lupus Erythematosus: A Preliminary Report , Stanford M. Bull. 11:157-161 ( (Aug.) ) 1953. 9. Goldman, L.; Cole, D. P., and Preston, R. H.: Chloroquine Diphosphate in the Treatment of Discoid Lupus Erythematosus , J. A. M. A. 152:1428-1429 ( (Aug. 8) ) 1953.Crossref 10. Hathaway, J. C.: Therapeutic Committee Evaluation Report: The Value of Atabrine Therapy in Chronic Discoid Lupus Erythematosus , Tr. Pacific Dermat. A. (6th Annual Meeting) 1:40-41, 1954. 11. Herrmann, F., and Miller, O. B.: Pharmacologic and Pathogenic Effects of Mepacrine Hydrochloride (Atabrine®) on Human Skin. I. Clinical and Experimental Observations , Acta dermat.-venereol. 32:304-316 1952. 12. II. Microscopic Studies of Vital Staining Effects in Skin , Herrmann Acta dermat.-venereol. 32:317-332, 1952. 13. Novy, F. G., Jr.: Therapeutic Committee Evaluation Report: Chloroquine Therapy and Discoid Lupus Erythematosus , Tr. Pacific Dermat. A. (6th Annual Meeting) 1:37-39, 1954. 14. Ottolenghi-Lodigiani, F.: Treatment of Chronic Lupus Erythematodes: Local Intradermal Infiltration with Acridine Preparations , Hautarzt 6:24-27 ( (Jan.) ) 1955. 15. Page, F.: Treatment of Lupus Erythematosus with Mepacrine , Lancet , 2:755-758 ( (Oct. 27) ) 1951.Crossref 16. Parmer, L. G., and Sawitsky, A.: Fatal Aplastic Anemia Following Quinacrine Therapy in Chronic Discoid Lupus Erythematosus , J. A. M. A. 153:1172-1174 ( (Nov. 28) ) 1953.Crossref 17. Pillsbury, D. M., and Jacobson, C.: Treatment of Chronic Discoid Lupus Erythematosus with Chloroquine (Aralen) J. A. M. A. 154:1330-1333 ( (April 17) ) 1954.Crossref 18. Popoff, L., and Kutinscheff: Case Presentations , Dermat. Wchnschr. 116:186, 1943. 19. Prokoptchouk, A. J.: Treatment of Lupus Erythematosus with Acriquine , Vestnik venerol. i dermat. , No. (2) -3, pp. 23-26, 1940; 20. abstracted, Zentralbl. Haut. u. Geschlechtskr. 66:112, 1940-1941. 21. Rhodes, B. L., and Allende, M. F.: Treatment of Chronic Discoid Lupus Erythematosus with Quinacrine , California Med. 80:70-71 ( (Feb.) ) 1954. 22. Rogers, J., and Finn, O. A.: Synthetic Antimalarial Drugs in Chronic Discoid Lupus Erythematosus and Light Eruptions , A. M. A. Arch. Dermat. & Syph. 70:61-66 ( (July) ) 1954. 23. Sawicky, H. H.; Kanof, N. B.; Silverberg, M. G.; Braitman, M., and Kalish, K.: Therapeutic Assays of the Skin and Cancer Unit of the New York Hospital: Assay VII. Quinacrine Hydrochloride (Atabrine Hydrochloride) for Chronic Discoid Lupus Erythematosus , J. Invest. Dermat. 19:397-404 ( (Dec.) ) 1952. 24. Sommerville, J.; Devine, D. C., and Logan, J. C. P.: Lupus Erythematosus Treated with Mepacrine , Brit. J. Dermat. 64:417-419 ( (Nov.) ) 1952.Crossref 25. Sulzberger, M. B., and Baer, R. L.: Editorial comment, The 1952 Year Book of Dermatology and Syphilology , Chicago, The Year Book Publishers, Inc., 1953, p. 92. 26. Tye, M. J.; Schiff, B. L.; Collins, S. F.; Baler, G. R., and Appel, B.: Chronic Discoid Lupus Erythematosus: Treatment with Daraprim and Chloroquin Diphosphate (Aralen) , New England J. Med. 251:52-55 ( (July 8) ) 1954.Crossref 27. Wells, G. C.: Treatment of Chronic Discoid Lupus Erythematosus with Atabrine , J. Invest. Dermat. 19:405-407 ( (Dec.) ) 1952.Crossref 28. Zakon, S. J., and Gershenson, J.: Introduction of Quinacrine in Treatment of Lupus Erythematosus , A. M. A. Arch. Dermat. 71:520-521 ( (April) ) 1955.Crossref
A.M.A. Archives of Dermatology – American Medical Association
Published: Jan 1, 1956
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