Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You and Your Team.

Learn More →

Antiemetic Effect of Droperidol After Ophthalmic Surgery

Antiemetic Effect of Droperidol After Ophthalmic Surgery Abstract • Postoperative nausea with emesis is an undesirable side effect of general anesthesia in patients who have undergone ophthalmic surgery. The antiemetic effect of intravenous droperidol (Inapsine) was measured in a double-blind, controlled study of 78 patients undergoing general (enflurane [Ethrane]) anesthesia for a variety of ophthalmic procedures. There was a significant difference in the incidence of postoperative nausea and/or emesis in the droperidol-treated group, 13 of 78 (16%) as compared with the control population (37 of 87 [42%]). No complications of droperidol administration were observed. Droperidol may be an effective antiemetic drug if used prophylactically in patients who receive general anesthesia for ophthalmic surgery. References 1. Smessaert A, Schehr CA, Artusio JF Jr: Nausea and vomiting in the immediate postanesthetic period . JAMA 170:2072-2076, 1959.Crossref 2. Nikki P, Pohjola S: Nausea and vomiting after ocular surgery . Acta Ophthalmol 50: 525-531, 1972.Crossref 3. Borchert K, Dauss I: Problematik des postnarkotischen erbrechens nach augenoperationen . Klin Monatshl Augenheilkd 158:450-454, 1971. 4. Morrison JD, Clark RSJ, Dundee JW: Studies of drugs given before anaesthesia: XXI. Droperidol . Br J Anaesth 42: 730-735, 1970.Crossref 5. Patton CM Jr, Moon MR, Dannemiller FJ: The prophylactic antiemetic effect of droperidol . Anesth Analg 53:361-364, 1974. 6. Bellville JW: Postanesthetic nausea and vomiting . Anesthesiology 22:773-780, 1961.Crossref 7. Knapp MR, Beecher HK: Postanesthetic nausea, vomiting, and retching . JAMA 160:376-384, 1956.Crossref 8. Burtless R, Peckett BW: Postoperative vomiting: Some factors affecting its incidence . Br J Anaesth 29:114-123, 1957.Crossref 9. Scurr CF, Robbie DS: Trials of perphenazine in the prevention of postoperative vomiting . Br Med J 1:922-923, 1958.Crossref 10. Riding JE: Postoperative vomiting . Proc R Soc Med 53:671-677, 1960. 11. Dobkin AB, Heinrich RG, Israel JS, et al: Clinical and laboratory evaluation of a new inhalation agent: Compound 347 (CHF2-0-CF2-CHFCl) . Anesthesiology 29:275-282, 1968.Crossref 12. Soudijn W, Wijngaarden JV, Janssen PAJ: Biotransformation of neuroleptanalgesics . Int Anesthesiol Clin 12:145-155, 1974.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Antiemetic Effect of Droperidol After Ophthalmic Surgery

Loading next page...
 
/lp/american-medical-association/antiemetic-effect-of-droperidol-after-ophthalmic-surgery-60FvVX3cWZ
Publisher
American Medical Association
Copyright
Copyright © 1978 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1978.03910060132007
Publisher site
See Article on Publisher Site

Abstract

Abstract • Postoperative nausea with emesis is an undesirable side effect of general anesthesia in patients who have undergone ophthalmic surgery. The antiemetic effect of intravenous droperidol (Inapsine) was measured in a double-blind, controlled study of 78 patients undergoing general (enflurane [Ethrane]) anesthesia for a variety of ophthalmic procedures. There was a significant difference in the incidence of postoperative nausea and/or emesis in the droperidol-treated group, 13 of 78 (16%) as compared with the control population (37 of 87 [42%]). No complications of droperidol administration were observed. Droperidol may be an effective antiemetic drug if used prophylactically in patients who receive general anesthesia for ophthalmic surgery. References 1. Smessaert A, Schehr CA, Artusio JF Jr: Nausea and vomiting in the immediate postanesthetic period . JAMA 170:2072-2076, 1959.Crossref 2. Nikki P, Pohjola S: Nausea and vomiting after ocular surgery . Acta Ophthalmol 50: 525-531, 1972.Crossref 3. Borchert K, Dauss I: Problematik des postnarkotischen erbrechens nach augenoperationen . Klin Monatshl Augenheilkd 158:450-454, 1971. 4. Morrison JD, Clark RSJ, Dundee JW: Studies of drugs given before anaesthesia: XXI. Droperidol . Br J Anaesth 42: 730-735, 1970.Crossref 5. Patton CM Jr, Moon MR, Dannemiller FJ: The prophylactic antiemetic effect of droperidol . Anesth Analg 53:361-364, 1974. 6. Bellville JW: Postanesthetic nausea and vomiting . Anesthesiology 22:773-780, 1961.Crossref 7. Knapp MR, Beecher HK: Postanesthetic nausea, vomiting, and retching . JAMA 160:376-384, 1956.Crossref 8. Burtless R, Peckett BW: Postoperative vomiting: Some factors affecting its incidence . Br J Anaesth 29:114-123, 1957.Crossref 9. Scurr CF, Robbie DS: Trials of perphenazine in the prevention of postoperative vomiting . Br Med J 1:922-923, 1958.Crossref 10. Riding JE: Postoperative vomiting . Proc R Soc Med 53:671-677, 1960. 11. Dobkin AB, Heinrich RG, Israel JS, et al: Clinical and laboratory evaluation of a new inhalation agent: Compound 347 (CHF2-0-CF2-CHFCl) . Anesthesiology 29:275-282, 1968.Crossref 12. Soudijn W, Wijngaarden JV, Janssen PAJ: Biotransformation of neuroleptanalgesics . Int Anesthesiol Clin 12:145-155, 1974.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Aug 1, 1978

References