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ANTICOAGULANTS IN CORONARY THROMBOSIS WITH MYOCARDIAL INFARCTION

ANTICOAGULANTS IN CORONARY THROMBOSIS WITH MYOCARDIAL INFARCTION Abstract THE RECOMMENDATION for the use of anticoagulants in the management of patients with myocardial infarction is based largely on the progress report1 of the American Heart Association's Committee for the Evaluation of Anticoagulants in the Treatment of Coronary Thrombosis with Myocardial Infarction. Subsequent to editorial comments2 two years ago, members of the Committee published additional data3 which appear to confirm the earlier recommendation. Largely because of the general acceptance of the Committee's conclusions, physicians who disagree find themselves under a certain amount of pressure from their colleagues to use anticoagulants; this is so even though at the Twenty-Third Scientific Sessions of the American Heart Association on June 23, 1950, the chairman of a panel on modern treatment of cardiovascular diseases announced that none of the panel members used anticoagulants routinely in treating patients with myocardial infarction. There appear to be "one or two disturbing features"4 of References 1. Wright, I. S.; Marple, C. D., and Beck, D. F.: Anticoagulant Therapy of Coronary Thrombosis with Myocardial Infarction , J. A. M. A. 138:1074 ( (Dec. 11) ) 1948.Crossref 2. Anticoagulants in Coronary Thrombosis with Myocardial Infarction, editorial , J. A. M. A. 139:1274 ( (April 30) ) 1949. 3. Wright, I. S.; Marple, C. D., and Beck, D. F.: The Use of Anticoagulants in the Treatment of Myocardial Infarction , Mod. Concepts Cardiovas. Dis. 18:55 ( (Dec.) ) 1949. 4. Anticoagulant Therapy of Acute Myocardial Infarction , Brit. M. J. 2:991 ( (Oct. 28) ) 1950.Crossref 5. Billings, F. T., Jr.; Kalstone, B. M.; Spencer, J. L.; Ball, C. O. T., and Meneely, G. R.: Prognosis of Acute Myocardial Infarction , Am. J. Med. 7:356 ( (Sept.) ) 1949.Crossref 6. Doscher, N., and Poindexter, C. A.: Myocardial Infarction Without Anticoagulant Therapy: Deaths, Emboli and an Analysis of Factors Influencing Mortality , Am. J. Med. 8:623 ( (May) ) 1950.Crossref 7. Russek, H. I.; Zohman, B. L.; White, L. G., and Doerner, A. A.: Indications for Bishydroxycoumarin (Dicumarol®) in Acute Myocardial Infarction , J. A. M. A. 145:390 ( (Feb. 10) ) 1951.Crossref 8. Rosenbaum, F. F., and Levine, S. A.: Prognostic Value of Various Clinical and Electrocardiographic Features of Acute Myocardial Infarction: I. Immediate Prognosis , Arch. Int. Med. 68:913 ( (Nov.) ) 1941.Crossref 9. Levine, S. A., and Rosenbaum, F. F.: Prognostic Value of Various Clinical and Electrocardiographic Features of Acute Myocardial Infarction: II. Ultimate Prognosis , Arch. Int. Med. 68:1215 ( (Dec.) ) 1941.Crossref 10. Master, A. M.; Jaffe, H. L., and Dack, S.: The Treatment and the Immediate Prognosis of Coronary Artery Thrombosis: 267 Attacks , Am. Heart J. 12:549 ( (Nov.) ) 1936.Crossref 11. Newman, M.: Coronary Occlusion in Young Adults: A Review of 50 Cases in the Services , Lancet 2:409 ( (Sept. 21) ) 1946.Crossref 12. Marple, C. D.: Anticoagulant Therapy in Heart Disease: A Summary of the Literature , California Med. 73:425 ( (Nov.) ) 1950. 13. Hellerstein, H. K., and Martin, J. W.: Incidence of Thrombo-Embolic Lesions Accompanying Myocardial Infarction , Am. Heart J. 33:443 ( (April) ) 1947.Crossref 14. Bresnick, E.; Selverstone, L. A.; Rapoport, B.; Cheskey, K.; Hultgren, H. N., and Sise, H. S.: Experiences with Dicumarol in Acute Myocardial Infarction , New England J. Med. 243:806 ( (Nov. 23) ) 1950.Crossref 15. Harvey, W. P., and Finch, C. A.: Dicumarol Prophylaxis of Thromboembolic Disease in Congestive Heart Failure , New England J. Med. 242:208 ( (Feb. 9) ) 1950.Crossref 16. Dr. Charles W. Barnett aided in the statistical analysis. 17. Dale, D. U., and Jaques, L. B.: The Prevention of Experimental Thrombosis by Dicoumarin , Canad. M. A. J. 46:546 ( (June) ) 1942. 18. Schilling, F. J.: Anticoagulants in Myocardial Infarction , J. A. M. A. 143:785 ( (July 1) ) 1950.Crossref 19. Gilbert, N. C.; Fenn, G. K., and Nalefski, L. A.: Role of Vasodilator Drugs in Coronary Occlusion , J. A. M. A. 141:892 ( (Nov. 26) ) 1949.Crossref 20. Parker, R. L., and Barker, N. W.: The Effect of Anticoagulants on the Incidence of Thrombo-Embolic Complications in Acute Myocardial Infarction , Proc. Staff Meet., Mayo Clin. 23:367 ( (Aug. 4) ) 1948. 21. Tulloch, J. A., and Gilchrist, A. R.: Anticoagulants in Treatment of Coronary Thrombosis , Brit. M. J. 2:965 ( (Oct. 28) ) 1950.Crossref 22. Anticoagulants as a Cause of Hemorrhage , J. A. M. A. 144:1466 ( (Dec. 23) ) 1950. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Archives of Internal Medicine American Medical Association

ANTICOAGULANTS IN CORONARY THROMBOSIS WITH MYOCARDIAL INFARCTION

RYTAND, DAVID A.
A.M.A. Archives of Internal Medicine , Volume 88 (2) – Aug 1, 1951
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American Medical Association
Copyright
Copyright © 1951 American Medical Association. All Rights Reserved.
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0888-2479
DOI
10.1001/archinte.1951.03810080075008
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Abstract

Abstract THE RECOMMENDATION for the use of anticoagulants in the management of patients with myocardial infarction is based largely on the progress report1 of the American Heart Association's Committee for the Evaluation of Anticoagulants in the Treatment of Coronary Thrombosis with Myocardial Infarction. Subsequent to editorial comments2 two years ago, members of the Committee published additional data3 which appear to confirm the earlier recommendation. Largely because of the general acceptance of the Committee's conclusions, physicians who disagree find themselves under a certain amount of pressure from their colleagues to use anticoagulants; this is so even though at the Twenty-Third Scientific Sessions of the American Heart Association on June 23, 1950, the chairman of a panel on modern treatment of cardiovascular diseases announced that none of the panel members used anticoagulants routinely in treating patients with myocardial infarction. There appear to be "one or two disturbing features"4 of References 1. Wright, I. S.; Marple, C. D., and Beck, D. F.: Anticoagulant Therapy of Coronary Thrombosis with Myocardial Infarction , J. A. M. A. 138:1074 ( (Dec. 11) ) 1948.Crossref 2. Anticoagulants in Coronary Thrombosis with Myocardial Infarction, editorial , J. A. M. A. 139:1274 ( (April 30) ) 1949. 3. Wright, I. S.; Marple, C. D., and Beck, D. F.: The Use of Anticoagulants in the Treatment of Myocardial Infarction , Mod. Concepts Cardiovas. Dis. 18:55 ( (Dec.) ) 1949. 4. Anticoagulant Therapy of Acute Myocardial Infarction , Brit. M. J. 2:991 ( (Oct. 28) ) 1950.Crossref 5. Billings, F. T., Jr.; Kalstone, B. M.; Spencer, J. L.; Ball, C. O. T., and Meneely, G. R.: Prognosis of Acute Myocardial Infarction , Am. J. Med. 7:356 ( (Sept.) ) 1949.Crossref 6. Doscher, N., and Poindexter, C. A.: Myocardial Infarction Without Anticoagulant Therapy: Deaths, Emboli and an Analysis of Factors Influencing Mortality , Am. J. Med. 8:623 ( (May) ) 1950.Crossref 7. Russek, H. I.; Zohman, B. L.; White, L. G., and Doerner, A. A.: Indications for Bishydroxycoumarin (Dicumarol®) in Acute Myocardial Infarction , J. A. M. A. 145:390 ( (Feb. 10) ) 1951.Crossref 8. Rosenbaum, F. F., and Levine, S. A.: Prognostic Value of Various Clinical and Electrocardiographic Features of Acute Myocardial Infarction: I. Immediate Prognosis , Arch. Int. Med. 68:913 ( (Nov.) ) 1941.Crossref 9. Levine, S. A., and Rosenbaum, F. F.: Prognostic Value of Various Clinical and Electrocardiographic Features of Acute Myocardial Infarction: II. Ultimate Prognosis , Arch. Int. Med. 68:1215 ( (Dec.) ) 1941.Crossref 10. Master, A. M.; Jaffe, H. L., and Dack, S.: The Treatment and the Immediate Prognosis of Coronary Artery Thrombosis: 267 Attacks , Am. Heart J. 12:549 ( (Nov.) ) 1936.Crossref 11. Newman, M.: Coronary Occlusion in Young Adults: A Review of 50 Cases in the Services , Lancet 2:409 ( (Sept. 21) ) 1946.Crossref 12. Marple, C. D.: Anticoagulant Therapy in Heart Disease: A Summary of the Literature , California Med. 73:425 ( (Nov.) ) 1950. 13. Hellerstein, H. K., and Martin, J. W.: Incidence of Thrombo-Embolic Lesions Accompanying Myocardial Infarction , Am. Heart J. 33:443 ( (April) ) 1947.Crossref 14. Bresnick, E.; Selverstone, L. A.; Rapoport, B.; Cheskey, K.; Hultgren, H. N., and Sise, H. S.: Experiences with Dicumarol in Acute Myocardial Infarction , New England J. Med. 243:806 ( (Nov. 23) ) 1950.Crossref 15. Harvey, W. P., and Finch, C. A.: Dicumarol Prophylaxis of Thromboembolic Disease in Congestive Heart Failure , New England J. Med. 242:208 ( (Feb. 9) ) 1950.Crossref 16. Dr. Charles W. Barnett aided in the statistical analysis. 17. Dale, D. U., and Jaques, L. B.: The Prevention of Experimental Thrombosis by Dicoumarin , Canad. M. A. J. 46:546 ( (June) ) 1942. 18. Schilling, F. J.: Anticoagulants in Myocardial Infarction , J. A. M. A. 143:785 ( (July 1) ) 1950.Crossref 19. Gilbert, N. C.; Fenn, G. K., and Nalefski, L. A.: Role of Vasodilator Drugs in Coronary Occlusion , J. A. M. A. 141:892 ( (Nov. 26) ) 1949.Crossref 20. Parker, R. L., and Barker, N. W.: The Effect of Anticoagulants on the Incidence of Thrombo-Embolic Complications in Acute Myocardial Infarction , Proc. Staff Meet., Mayo Clin. 23:367 ( (Aug. 4) ) 1948. 21. Tulloch, J. A., and Gilchrist, A. R.: Anticoagulants in Treatment of Coronary Thrombosis , Brit. M. J. 2:965 ( (Oct. 28) ) 1950.Crossref 22. Anticoagulants as a Cause of Hemorrhage , J. A. M. A. 144:1466 ( (Dec. 23) ) 1950.

Journal

A.M.A. Archives of Internal Medicine – American Medical Association

Published: Aug 1, 1951

References

  • Anticoagulant Therapy of Coronary Thrombosis with Myocardial Infarction
    Wright , I. S.; Marple, C. D., and Beck, D. F.
  • Anticoagulants in Coronary Thrombosis with Myocardial Infarction, editorial
  • The Use of Anticoagulants in the Treatment of Myocardial Infarction
    Wright , I. S.; Marple, C. D., and Beck, D. F.
  • Anticoagulant Therapy of Acute Myocardial Infarction
  • Prognosis of Acute Myocardial Infarction
    Billings , F. T., Jr.; Kalstone, B. M.; Spencer, J. L.; Ball, C. O. T., and Meneely, G. R.
  • Myocardial Infarction Without Anticoagulant Therapy: Deaths, Emboli and an Analysis of Factors Influencing Mortality
    Doscher , N., and Poindexter, C. A.
  • Indications for Bishydroxycoumarin (Dicumarol®) in Acute Myocardial Infarction
    Russek , H. I.; Zohman, B. L.; White, L. G., and Doerner, A. A.
  • Prognostic Value of Various Clinical and Electrocardiographic Features of Acute Myocardial Infarction: I. Immediate Prognosis
    Rosenbaum , F. F., and Levine, S. A.
  • Prognostic Value of Various Clinical and Electrocardiographic Features of Acute Myocardial Infarction: II. Ultimate Prognosis
    Levine , S. A., and Rosenbaum, F. F.
  • The Treatment and the Immediate Prognosis of Coronary Artery Thrombosis: 267 Attacks
    Master , A. M.; Jaffe, H. L., and Dack, S.
  • Coronary Occlusion in Young Adults: A Review of 50 Cases in the Services
    Newman , M.
  • Anticoagulant Therapy in Heart Disease: A Summary of the Literature
    Marple , C. D.
  • Incidence of Thrombo-Embolic Lesions Accompanying Myocardial Infarction
    Hellerstein , H. K., and Martin, J. W.
  • Experiences with Dicumarol in Acute Myocardial Infarction
    Bresnick , E.; Selverstone, L. A.; Rapoport, B.; Cheskey, K.; Hultgren, H. N., and Sise, H. S.
  • Dicumarol Prophylaxis of Thromboembolic Disease in Congestive Heart Failure
    Harvey , W. P., and Finch, C. A.
  • The Prevention of Experimental Thrombosis by Dicoumarin
    Dale , D. U., and Jaques, L. B.
  • Anticoagulants in Myocardial Infarction
    Schilling , F. J.
  • Role of Vasodilator Drugs in Coronary Occlusion
    Gilbert , N. C.; Fenn, G. K., and Nalefski, L. A.
  • The Effect of Anticoagulants on the Incidence of Thrombo-Embolic Complications in Acute Myocardial Infarction
    Parker , R. L., and Barker, N. W.
  • Anticoagulants in Treatment of Coronary Thrombosis
    Tulloch , J. A., and Gilchrist, A. R.
  • Anticoagulants as a Cause of Hemorrhage