STUDY ONLINE FIRST Antibiotics, Acne, and Staphylococcus aureus Colonization Matthew Fanelli, MD; Eli Kupperman, BA; Ebbing Lautenbach, MD, MPH; Paul H. Edelstein, MD; David J. Margolis, MD, PhD Objectives: To determine the frequency of Staphylo- and 7 (19%) had S aureus in both their nose and their coccus aureus colonization among patients with acne and throat. When patients with acne who were antibiotic us- to compare the susceptibility patterns between the pa- ers were compared with nonusers, the prevalence odds tients who are using antibiotics and those who are not ratio for the colonization of S aureus was 0.16 (95% con- using antibiotics. fidence interval [CI], 0.08-1.37) after 1 to 2 months of exposure and increased to 0.52 (95% CI, 0.12-2.17) af- Design: Survey (cross-sectional) study of patients treated ter 2 months of exposure (P=.31). Many of the S aureus for acne. isolates were resistant to treatment with clindamycin and erythromycin (40% and 44%, respectively), particularly Setting: Dermatology outpatient office practice the nasal isolates. Very few showed resistance rates (10%) to treatment with tetracycline antibiotics. Participants: The study included 83 patients who were undergoing treatment and evaluation for acne. Conclusion: Unlike current dogma about the long- term use of
JAMA Dermatology – American Medical Association
Published: Aug 1, 2011
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