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Angiosarcoma of the Nose

Angiosarcoma of the Nose Abstract Angiosarcoma presenting as a tumor of the nose is extremely rare. Recently, such a case was encountered in our institution. Report of a Case A 72-year-old man was admitted to the hospital with a one-year history of a slowly enlarging lesion of his nose. Previously, he had been admitted to another hospital, where he had undergone multiple biopsies of the lesion. The biopsies were variously interpreted as pyogenic granuloma, lethal midline granuloma, and squamous cell carcinoma.On physical examination, the distal third of the nose showed a dark, firm, infiltrative lesion extending into the nasal cavities (Fig 1). The skin showed ulcerated areas, blood clots, and peripheral ill-defined purple-blue infiltrations. Palpable, hard lymph nodes, measuring up to 1.5 cm in diameter, were present in the submental and submandibular areas bilaterally. The rest of the physical findings were noncontributory. Roentgenograms and scans failed to show any evidence of distant metastasis.Because References 1. Landells JW: Malignant tumors of the heart and blood vessels . Cancer. Washington, DC, Butterworth Inc, 1958, vol 2, pp 512-524. 2. Stout AP, Lattes R: Tumors of the Soft Tissues . Atlas of Tumor Pathology, Armed Forces Institute of Pathology, 1967, section 2, pt (1) , p 145. 3. Rosai J, Summer JW, Kostianovsky M, et al: Angiosarcoma of the skin: A clinicopathologic and fine structural study . Hum Pathol 7:83-109, 1976.Crossref 4. McCarthy WD, Pack GT: Malignant blood vessel tumors: A report of 56 cases of angiosarcoma and Kaposi's sarcoma . Surg Gynecol Obstet 91:465-482, 1950. 5. Girard C, Johnson WC, Graham JH: Cutaneous angiosarcomas . Cancer 26:868-883, 1970.Crossref 6. Jones EW: Malignant angioendothelioma of the skin . Br J Dermatol 76:21-39, 1964.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Angiosarcoma of the Nose

Archives of Dermatology , Volume 116 (2) – Feb 1, 1980

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Publisher
American Medical Association
Copyright
Copyright © 1980 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1980.01640260102027
Publisher site
See Article on Publisher Site

Abstract

Abstract Angiosarcoma presenting as a tumor of the nose is extremely rare. Recently, such a case was encountered in our institution. Report of a Case A 72-year-old man was admitted to the hospital with a one-year history of a slowly enlarging lesion of his nose. Previously, he had been admitted to another hospital, where he had undergone multiple biopsies of the lesion. The biopsies were variously interpreted as pyogenic granuloma, lethal midline granuloma, and squamous cell carcinoma.On physical examination, the distal third of the nose showed a dark, firm, infiltrative lesion extending into the nasal cavities (Fig 1). The skin showed ulcerated areas, blood clots, and peripheral ill-defined purple-blue infiltrations. Palpable, hard lymph nodes, measuring up to 1.5 cm in diameter, were present in the submental and submandibular areas bilaterally. The rest of the physical findings were noncontributory. Roentgenograms and scans failed to show any evidence of distant metastasis.Because References 1. Landells JW: Malignant tumors of the heart and blood vessels . Cancer. Washington, DC, Butterworth Inc, 1958, vol 2, pp 512-524. 2. Stout AP, Lattes R: Tumors of the Soft Tissues . Atlas of Tumor Pathology, Armed Forces Institute of Pathology, 1967, section 2, pt (1) , p 145. 3. Rosai J, Summer JW, Kostianovsky M, et al: Angiosarcoma of the skin: A clinicopathologic and fine structural study . Hum Pathol 7:83-109, 1976.Crossref 4. McCarthy WD, Pack GT: Malignant blood vessel tumors: A report of 56 cases of angiosarcoma and Kaposi's sarcoma . Surg Gynecol Obstet 91:465-482, 1950. 5. Girard C, Johnson WC, Graham JH: Cutaneous angiosarcomas . Cancer 26:868-883, 1970.Crossref 6. Jones EW: Malignant angioendothelioma of the skin . Br J Dermatol 76:21-39, 1964.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Feb 1, 1980

References