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An Update of the Indications for Penetrating Keratoplasty: 1979 Through 1983

An Update of the Indications for Penetrating Keratoplasty: 1979 Through 1983 Abstract • We performed a retrospective analysis of the clinical and pathologic diagnoses of 497 corneal buttons that had been submitted to the Estelle Doheny Eye Pathology Laboratory, Los Angeles, during the five-year period 1979 through 1983. The leading indications, in order of decreasing frequency, were pseudophakic bullous keratopathy (17.5%), regrafts (15.1%), aphakic bullous keratopathy (10.9%), corneal trauma (9.3%), and Fuchs' endothelial dystrophy (9.1%). The emergence of pseudophakic bullous keratopathy as the most common cause for penetrating keratoplasty correlates well with the dramatic increase in the number of cataract extractions with intraocular lens implantations performed since the mid-1970s. Less frequent indications for penetrating keratoplasty included the following: corneal scars (6%); active ulcerative keratitis (7%); keratoconus (6%); keratitis secondary to virus (5%); non-Fuchs' corneal dystrophies (3%); congenital corneal opacities (3%); interstitial keratitis (2%); and chemical burns (1%). References 1. Arentsen JJ, Morgan B, Green WR: Changing indications for keratoplasty . Am J Ophthalmol 1976;81:313-318. 2. Smith RE, McDonald HR, Nesburn AB, et al: Penetrating keratoplasty: Changing indications, 1947 to 1978 . Arch Ophthalmol 1980; 98:1226-1229.Crossref 3. Lemp MA: Indications for penetrating keratoplasty . Med Ann DC 1972;41:346-350. 4. Chandler JW: Indications for penetrating keratoplasty and management of cases . Trans Pac Coast Oto-Ophthalmol Soc 1976;57:97-104. 5. Rabb MF, Fine M: Penetrating keratoplasty in interstitial keratitis . Am J Ophthalmol 1969;67:907-917. 6. Brown SI, Tragakis MP, Pearce DB: Corneal transplantation for severe alkali burns . Trans Am Acad Ophthalmol Otolaryngol 1972;76:1266-1274. 7. Tragakis MP, Rosen J, Brown SI: Transplantation of the perforated cornea . Am J Ophthalmol 1974;78:518-522. 8. Fine M, Cignetti FE: Penetrating keratoplasty in herpes simplex keratitis . Arch Ophthalmol 1977;95:613-616.Crossref 9. Sanders N: Penetrating keratoplasty in treatment of fungus keratitis . Am J Ophthalmol 1970;70:24-30. 10. Waring GO III: Selecting patients for penetrating keratoplasty . South Med J 1981;74:1243-1248.Crossref 11. Schanzlin DJ, Robin JB, Gomez DS, et al: Results of penetrating keratoplasty for aphakic and pseudophakic bullous keratopathy . Am J Ophthalmol 1984;98:302-312. 12. Robinson CH Jr: Indications, complications and prognosis for repeat penetrating keratoplasty . Ophthalmic Surg 1979;10:27-34. 13. Foster CS, Duncan J: Penetrating keratoplasty for herpes simplex keratitis . Am J Ophthalmol 1981;92:336-343. 14. Gordon YJ, Mokete M: Penetrating keratoplasty in children . J Pediatr Ophthalmol Strabismus 1979;16:297-300. 15. Stark WJ, Leske MC, Worthen DM, et al: Trends in cataract surgery and intraocular lenses in the United States . Am J Ophthalmol 1983;96:304-310. 16. Meyer RF, Sugar A: Penetrating keratoplasty in pseudophakic bullous keratopathy . Am J Ophthalmol 1980;90:677-681. 17. Taylor DM, Atlas BF, Romanchuk KG, et al: Pseudophakic bullous keratopathy . Ophthalmology 1983;90:19-24.Crossref 18. Waring GO III, Welch SN, Cavanagh HD, et al: Results of penetrating keratoplasty in 123 eyes with pseudophakic or aphakic corneal edema . Ophthalmology 1983;90:25-33.Crossref 19. Olson RJ, Waltman SR, Mattingly TP, et al: Visual results after penetrating keratoplasty for aphakic bullous keratopathy and Fuchs' dystrophy . Am J Ophthalmol 1979;88:1000-1004. 20. Arentsen JJ, Laibson PR: Surgical management of pseudophakic corneal edema: Complications and visual results . Ophthalmic Surg 1982;13:371-373. 21. Stark WJ, Maumenee AE: Update of the intraocular lens: Experience at the Wilmer Institute . Ophthalmologica 1983;187:65-73.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

An Update of the Indications for Penetrating Keratoplasty: 1979 Through 1983

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Publisher
American Medical Association
Copyright
Copyright © 1986 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1986.01050130097029
Publisher site
See Article on Publisher Site

Abstract

Abstract • We performed a retrospective analysis of the clinical and pathologic diagnoses of 497 corneal buttons that had been submitted to the Estelle Doheny Eye Pathology Laboratory, Los Angeles, during the five-year period 1979 through 1983. The leading indications, in order of decreasing frequency, were pseudophakic bullous keratopathy (17.5%), regrafts (15.1%), aphakic bullous keratopathy (10.9%), corneal trauma (9.3%), and Fuchs' endothelial dystrophy (9.1%). The emergence of pseudophakic bullous keratopathy as the most common cause for penetrating keratoplasty correlates well with the dramatic increase in the number of cataract extractions with intraocular lens implantations performed since the mid-1970s. Less frequent indications for penetrating keratoplasty included the following: corneal scars (6%); active ulcerative keratitis (7%); keratoconus (6%); keratitis secondary to virus (5%); non-Fuchs' corneal dystrophies (3%); congenital corneal opacities (3%); interstitial keratitis (2%); and chemical burns (1%). References 1. Arentsen JJ, Morgan B, Green WR: Changing indications for keratoplasty . Am J Ophthalmol 1976;81:313-318. 2. Smith RE, McDonald HR, Nesburn AB, et al: Penetrating keratoplasty: Changing indications, 1947 to 1978 . Arch Ophthalmol 1980; 98:1226-1229.Crossref 3. Lemp MA: Indications for penetrating keratoplasty . Med Ann DC 1972;41:346-350. 4. Chandler JW: Indications for penetrating keratoplasty and management of cases . Trans Pac Coast Oto-Ophthalmol Soc 1976;57:97-104. 5. Rabb MF, Fine M: Penetrating keratoplasty in interstitial keratitis . Am J Ophthalmol 1969;67:907-917. 6. Brown SI, Tragakis MP, Pearce DB: Corneal transplantation for severe alkali burns . Trans Am Acad Ophthalmol Otolaryngol 1972;76:1266-1274. 7. Tragakis MP, Rosen J, Brown SI: Transplantation of the perforated cornea . Am J Ophthalmol 1974;78:518-522. 8. Fine M, Cignetti FE: Penetrating keratoplasty in herpes simplex keratitis . Arch Ophthalmol 1977;95:613-616.Crossref 9. Sanders N: Penetrating keratoplasty in treatment of fungus keratitis . Am J Ophthalmol 1970;70:24-30. 10. Waring GO III: Selecting patients for penetrating keratoplasty . South Med J 1981;74:1243-1248.Crossref 11. Schanzlin DJ, Robin JB, Gomez DS, et al: Results of penetrating keratoplasty for aphakic and pseudophakic bullous keratopathy . Am J Ophthalmol 1984;98:302-312. 12. Robinson CH Jr: Indications, complications and prognosis for repeat penetrating keratoplasty . Ophthalmic Surg 1979;10:27-34. 13. Foster CS, Duncan J: Penetrating keratoplasty for herpes simplex keratitis . Am J Ophthalmol 1981;92:336-343. 14. Gordon YJ, Mokete M: Penetrating keratoplasty in children . J Pediatr Ophthalmol Strabismus 1979;16:297-300. 15. Stark WJ, Leske MC, Worthen DM, et al: Trends in cataract surgery and intraocular lenses in the United States . Am J Ophthalmol 1983;96:304-310. 16. Meyer RF, Sugar A: Penetrating keratoplasty in pseudophakic bullous keratopathy . Am J Ophthalmol 1980;90:677-681. 17. Taylor DM, Atlas BF, Romanchuk KG, et al: Pseudophakic bullous keratopathy . Ophthalmology 1983;90:19-24.Crossref 18. Waring GO III, Welch SN, Cavanagh HD, et al: Results of penetrating keratoplasty in 123 eyes with pseudophakic or aphakic corneal edema . Ophthalmology 1983;90:25-33.Crossref 19. Olson RJ, Waltman SR, Mattingly TP, et al: Visual results after penetrating keratoplasty for aphakic bullous keratopathy and Fuchs' dystrophy . Am J Ophthalmol 1979;88:1000-1004. 20. Arentsen JJ, Laibson PR: Surgical management of pseudophakic corneal edema: Complications and visual results . Ophthalmic Surg 1982;13:371-373. 21. Stark WJ, Maumenee AE: Update of the intraocular lens: Experience at the Wilmer Institute . Ophthalmologica 1983;187:65-73.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jan 1, 1986

References