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America’s Cannabis Experiment

America’s Cannabis Experiment Editorial Opinion David Goldman, MD Cannabis is widely used, psychoactive, and addictive. Given The Vulnerable Brain the choice, people in several US states and the District of Co- Genotype and environment can be better controlled in ani- lumbia have voted to legalize it. In the nation’s capital, it is now mal models, leading to more consistency of effects, espe- legal to possess as many as 3 Cannabis sativa plants. Mean- cially on physiology. Humans are messier. Because of diver- while, it remains illegal to sity in genotype and environment, one person’s sugar may be have cannabis on federal another’s poison. Also in this issue, French and colleagues took Related articles pages 994 land, which is problematic in a very different approach to investigate the role of genotype and 1002 a mosaic of federal and local in the effects of cannabis on brain structure. In 3 longitudi- jurisdictions. Further, a fed- nally studied populations comprising more than 1500 adoles- eral worker stands to be fired if discovered to be using canna- cents, they found that a polygenic risk score for schizophre- bis. In the cannabis debate, does the science of consequences nia, a disease that may be triggered by cannabis, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA Psychiatry American Medical Association

America’s Cannabis Experiment

JAMA Psychiatry , Volume 72 (10) – Oct 1, 2015

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Publisher
American Medical Association
Copyright
Copyright 2015 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
2168-622X
eISSN
2168-6238
DOI
10.1001/jamapsychiatry.2015.1332
pmid
26308765
Publisher site
See Article on Publisher Site

Abstract

Editorial Opinion David Goldman, MD Cannabis is widely used, psychoactive, and addictive. Given The Vulnerable Brain the choice, people in several US states and the District of Co- Genotype and environment can be better controlled in ani- lumbia have voted to legalize it. In the nation’s capital, it is now mal models, leading to more consistency of effects, espe- legal to possess as many as 3 Cannabis sativa plants. Mean- cially on physiology. Humans are messier. Because of diver- while, it remains illegal to sity in genotype and environment, one person’s sugar may be have cannabis on federal another’s poison. Also in this issue, French and colleagues took Related articles pages 994 land, which is problematic in a very different approach to investigate the role of genotype and 1002 a mosaic of federal and local in the effects of cannabis on brain structure. In 3 longitudi- jurisdictions. Further, a fed- nally studied populations comprising more than 1500 adoles- eral worker stands to be fired if discovered to be using canna- cents, they found that a polygenic risk score for schizophre- bis. In the cannabis debate, does the science of consequences nia, a disease that may be triggered by cannabis,

Journal

JAMA PsychiatryAmerican Medical Association

Published: Oct 1, 2015

References