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Alopecia Areata

Alopecia Areata Abstract To the Editor.— The article by Hordinsky et al1 on suppressor cells and markers of autoimmunity of alopecia areata (AA) prompted us to report recent results obtained in the study of non-organ-specific autoantibodies in a larger series of patients.A total of 62 patients were studied: 42 (M/F ratio, 23/19) with AA, eight (3/5) with alopecia totalis (AT) and 12 (8/4) with alopecia universalis (AU). The median age was 30 years (8 to 62) for AA, 15 years (6 to 50) for AT and 22.5 (9 to 52) years for AU. No patient was under steroid treatment at the moment of the test and 37 of the 62 were receiving topical treatment (DNCB or squaric acid dibutylester). Most patients were in the "stable" category. Only two patients had clinical evidence of associated (thyroid) diseases.The overall prevalence of non-organ-specific autoantibodies tested with an indirect immunofluorescence method on rat substrates References 1. Hordinsky MK, Hallgren H, Nelson D, et al: Suppressor cell number and function in alopecia areata . Arch Dermatol 1984;120:188-194.Crossref 2. Friedmann PS: Alopecia areata and autoimmunity . Br J Dermatol 1981;105:153-157.Crossref 3. Cochran RE, Thomson J, MacSween RN: An autoantibody profile in alopecia totalis and diffuse alopecia . Br J Dermatol 1976;95:61-65.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatology American Medical Association

Alopecia Areata

Abstract

Abstract To the Editor.— The article by Hordinsky et al1 on suppressor cells and markers of autoimmunity of alopecia areata (AA) prompted us to report recent results obtained in the study of non-organ-specific autoantibodies in a larger series of patients.A total of 62 patients were studied: 42 (M/F ratio, 23/19) with AA, eight (3/5) with alopecia totalis (AT) and 12 (8/4) with alopecia universalis (AU). The median age was 30 years (8 to 62) for AA, 15 years (6 to 50) for AT and 22.5 (9...
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Publisher
American Medical Association
Copyright
Copyright © 1985 American Medical Association. All Rights Reserved.
ISSN
0003-987X
eISSN
1538-3652
DOI
10.1001/archderm.1985.01660020027005
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor.— The article by Hordinsky et al1 on suppressor cells and markers of autoimmunity of alopecia areata (AA) prompted us to report recent results obtained in the study of non-organ-specific autoantibodies in a larger series of patients.A total of 62 patients were studied: 42 (M/F ratio, 23/19) with AA, eight (3/5) with alopecia totalis (AT) and 12 (8/4) with alopecia universalis (AU). The median age was 30 years (8 to 62) for AA, 15 years (6 to 50) for AT and 22.5 (9 to 52) years for AU. No patient was under steroid treatment at the moment of the test and 37 of the 62 were receiving topical treatment (DNCB or squaric acid dibutylester). Most patients were in the "stable" category. Only two patients had clinical evidence of associated (thyroid) diseases.The overall prevalence of non-organ-specific autoantibodies tested with an indirect immunofluorescence method on rat substrates References 1. Hordinsky MK, Hallgren H, Nelson D, et al: Suppressor cell number and function in alopecia areata . Arch Dermatol 1984;120:188-194.Crossref 2. Friedmann PS: Alopecia areata and autoimmunity . Br J Dermatol 1981;105:153-157.Crossref 3. Cochran RE, Thomson J, MacSween RN: An autoantibody profile in alopecia totalis and diffuse alopecia . Br J Dermatol 1976;95:61-65.Crossref

Journal

Archives of DermatologyAmerican Medical Association

Published: Feb 1, 1985

References