Letters every event related to therapies. We believe that the observa- genic” on it—is that Vaseline baby petroleum jelly contains tion of HR might be because these patients followed up with fragrance while Vaseline original does not. When comparing dermatologists, which highlights the importance of monitor- a product such as Aveeno baby daily moisture lotion to the ing by a multidisciplinary team. counterpart marketed for adults (Aveeno daily moisturizing There must be different mechanisms in how the anti–PD-1 lotion), they contained identical potential allergens. pathway works in different types of cancer and among differ- A study published in 2016 performed a systematic re- ent people. This might explain vitiligolike reactions in patients view of patch test results in children and adolescents with der- with melanoma and the opposite effect of HR in lung cancer, matitis and found that the top 5 most common allergens in chil- and now also in colorectal cancer or Hodgkin lymphoma. It also dren were nickel, thimerosal, cobalt, fragrance, and lanolin. may explain why some patients show HR, and some others who Yet, we found that many popular baby products contain lano- also had gray hair do not have HR. One hypothesis could be the
JAMA Dermatology – American Medical Association
Published: Jan 29, 2018
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