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Akinesia: A Poorly Recognized Drug-Induced Extrapyramidal Behavioral Disorder

Akinesia: A Poorly Recognized Drug-Induced Extrapyramidal Behavioral Disorder Abstract Akinesia is an extrapyramidal behavioral side-effect of antipsychotic medication characterized by a lessening of spontaneity, paucity of gestures, diminished conversation, and apathy. It can be easily confused with depression, demoralization, and residual schizophrenic defect. Studies of the value of maintenance antiparkinson medication usually overlook this common syndrome. We present eight case histories to illustrate this condition. References 1. Chien C, DiMascio A, Cole J: Antiparkinsonian agents and depot phenothiazine . Am J Psychiatry 131:86-90, 1974. 2. Klein DF, Davis JM: Diagnosis and Drug Treatment of Psychiatric Disorders . Baltimore, Williams & Wilkins Co, 1969, p 165. 3. DiMascio A: Towards a more rational use of antiparkinson drugs in psychiatry . Drug Therapy 1:23-29, 1971. 4. Mindham RHS, Gaind R, Anstee BH, et al: Comparison of amatadine, orphenadrine and placebo in the control of phenothiazine induced parkinsonism . Psychol Med 2:406-413, 1972.Crossref 5. Orlov P, Kasparian G, DiMascio A, et al: Withdrawal of antiparkinson drugs . Arch Gen Psychiatry 25:410-412, 1971.Crossref 6. Simpson GM, Angus JWS: Drug-induced extrapyramidal disorders . Acta Psychiatr Scand [Suppl] 212:17-19, 1970. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of General Psychiatry American Medical Association

Akinesia: A Poorly Recognized Drug-Induced Extrapyramidal Behavioral Disorder

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Publisher
American Medical Association
Copyright
Copyright © 1975 American Medical Association. All Rights Reserved.
ISSN
0003-990X
eISSN
1598-3636
DOI
10.1001/archpsyc.1975.01760230138011
Publisher site
See Article on Publisher Site

Abstract

Abstract Akinesia is an extrapyramidal behavioral side-effect of antipsychotic medication characterized by a lessening of spontaneity, paucity of gestures, diminished conversation, and apathy. It can be easily confused with depression, demoralization, and residual schizophrenic defect. Studies of the value of maintenance antiparkinson medication usually overlook this common syndrome. We present eight case histories to illustrate this condition. References 1. Chien C, DiMascio A, Cole J: Antiparkinsonian agents and depot phenothiazine . Am J Psychiatry 131:86-90, 1974. 2. Klein DF, Davis JM: Diagnosis and Drug Treatment of Psychiatric Disorders . Baltimore, Williams & Wilkins Co, 1969, p 165. 3. DiMascio A: Towards a more rational use of antiparkinson drugs in psychiatry . Drug Therapy 1:23-29, 1971. 4. Mindham RHS, Gaind R, Anstee BH, et al: Comparison of amatadine, orphenadrine and placebo in the control of phenothiazine induced parkinsonism . Psychol Med 2:406-413, 1972.Crossref 5. Orlov P, Kasparian G, DiMascio A, et al: Withdrawal of antiparkinson drugs . Arch Gen Psychiatry 25:410-412, 1971.Crossref 6. Simpson GM, Angus JWS: Drug-induced extrapyramidal disorders . Acta Psychiatr Scand [Suppl] 212:17-19, 1970.

Journal

Archives of General PsychiatryAmerican Medical Association

Published: May 1, 1975

References