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Aging, Cell Senescence, and Chronic Disease

Aging, Cell Senescence, and Chronic Disease This Viewpoint describes the processes by which aging of cells contributes to age-related decline, chronic disease, and multimorbidity, and describes current animal research and clinical trials investigating the effects of senolytic drugs and vaccines that target senescent cell antiapoptotic pathways and remove senescent cells. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Aging, Cell Senescence, and Chronic Disease

JAMA , Volume 320 (13) – Oct 2, 2018

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Publisher
American Medical Association
Copyright
Copyright 2018 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2018.12440
pmid
30242336
Publisher site
See Article on Publisher Site

Abstract

This Viewpoint describes the processes by which aging of cells contributes to age-related decline, chronic disease, and multimorbidity, and describes current animal research and clinical trials investigating the effects of senolytic drugs and vaccines that target senescent cell antiapoptotic pathways and remove senescent cells.

Journal

JAMAAmerican Medical Association

Published: Oct 2, 2018

References