Get 20M+ Full-Text Papers For Less Than $1.50/day. Start a 14-Day Trial for You or Your Team.

Learn More →

Adverse Reactions During Intravenous Fluorescein Angiography

Adverse Reactions During Intravenous Fluorescein Angiography Abstract To the Editor. —Intravenous (IV) fluorescein angiography has become a widely accepted diagnostic tool in ophthalmology since its description by Novatny and Alvis1 in 1961. Numerous adverse effects during fluorescein angiography, including allergic reaction, hypertensive crisis, and myocardial infarction have been reported. We prospectively observed and reported adverse reactions during fluorescein angiography among a series of 5,460 consecutive patients during a ten-year period.The first 2,360 consecutive patients received 5 mL of 10% fluorescein sodium. The subsequent 3,100 patients received 3 mL of 25% fluorescein sodium. All adverse effects reported by the patient and observed by the photographer were recorded (Table).The incidence of adverse effects using 10% dye was 9.2%, whereas the incidence with 25% dye was 9.5%. Nausea was the most common side effect of IV fluorescein angiography, occurring in 6% of all patients. Vomiting was uncommon, occurring in only 1%. There were five severe reactions References 1. Novatny HR, Alvis BZ: A method of photographing fluorescence in circulating blood in the human retina . Circulation 1961;24:82-86.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Adverse Reactions During Intravenous Fluorescein Angiography

Adverse Reactions During Intravenous Fluorescein Angiography

Abstract

Abstract To the Editor. —Intravenous (IV) fluorescein angiography has become a widely accepted diagnostic tool in ophthalmology since its description by Novatny and Alvis1 in 1961. Numerous adverse effects during fluorescein angiography, including allergic reaction, hypertensive crisis, and myocardial infarction have been reported. We prospectively observed and reported adverse reactions during fluorescein angiography among a series of 5,460 consecutive patients during a ten-year...
Loading next page...
 
/lp/american-medical-association/adverse-reactions-during-intravenous-fluorescein-angiography-NAaWnQ27ax
Publisher
American Medical Association
Copyright
Copyright © 1984 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1984.01040030651010
Publisher site
See Article on Publisher Site

Abstract

Abstract To the Editor. —Intravenous (IV) fluorescein angiography has become a widely accepted diagnostic tool in ophthalmology since its description by Novatny and Alvis1 in 1961. Numerous adverse effects during fluorescein angiography, including allergic reaction, hypertensive crisis, and myocardial infarction have been reported. We prospectively observed and reported adverse reactions during fluorescein angiography among a series of 5,460 consecutive patients during a ten-year period.The first 2,360 consecutive patients received 5 mL of 10% fluorescein sodium. The subsequent 3,100 patients received 3 mL of 25% fluorescein sodium. All adverse effects reported by the patient and observed by the photographer were recorded (Table).The incidence of adverse effects using 10% dye was 9.2%, whereas the incidence with 25% dye was 9.5%. Nausea was the most common side effect of IV fluorescein angiography, occurring in 6% of all patients. Vomiting was uncommon, occurring in only 1%. There were five severe reactions References 1. Novatny HR, Alvis BZ: A method of photographing fluorescence in circulating blood in the human retina . Circulation 1961;24:82-86.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jun 1, 1984

References