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Adrenochrome Pigmentation of Hydrophilic Lenses

Adrenochrome Pigmentation of Hydrophilic Lenses Abstract Brown-black pigmentation of hydrophilic lenses worn by three patients occurred within two months after concurrent epinephrine compound therapy was begun. In one case, dense pigmentation occurred in less than two weeks. Although no ocular damage resulted, considerable emotional trauma was experienced by one patient and his family prior to diagnosis of his apparently "black eye." In all cases the lenses were discarded. References 1. Löwenstein A: Künstliche Hervorrufung melanotischer Geschwülstchen in der Bindehaut . Ber Dtsch Ophthalmol Ges 46:439-441, 1927. 2. Veirs BR, McGrew JC: Ocular complications from topical epinephrine therapy of glaucoma . Eye Ear Nose Throat Mon 42:46-52, 1963. 3. Corwin ME, Spencer WH: Conjunctival melanin deposits, a side-effect of topical epinephrine therapy . Arch Ophthalmol 69:317-321, 1963.Crossref 4. Blobner E: Hornhautverfärbung durch ein Adrenalin präparat . Klin Monatsbl Augenheilkd 100:758-763, 1938. 5. Reinecke RD, Kuwabara T: Corneal deposits secondary to topical epinephrine . Am J Ophthalmol 70:170-172, 1963. 6. Ferry AP, Zimmerman LE: Black cornea: A complication of topical use of epinephrine . Am J Ophthalmol 58:205-210, 1964. 7. Cleasby G, Donaldson DD: Epinephrine pigmentation of the cornea . Arch Ophthalmol 78:74-75, 1967.Crossref 8. Green WR, Kaufer GJ, Dubroff, S: Black cornea, a complication of topical use of epinephrine . Ophthalmologica 154:88-95, 1967.Crossref 9. Madge GE, Geeraets WJ, Guerry D III: Black cornea secondary to topical epinephrine . Am J Ophthalmol 71:402-405, 1971. 10. Johnson BL, Buerger GF: Black orbital bone . Arch Ophthalmol 88:400-403, 1972.Crossref 11. Ferry JF: Black prosthesis, a complication of the topical use of epinephrine . Am J Ophthalmol 64:162, 1967. 12. Krejci L, Harrison R: Corneal pigment deposits from topically administered epinephrine: Experimental production . Arch Ophthalmol 82:836-839, 1969.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

Adrenochrome Pigmentation of Hydrophilic Lenses

Archives of Ophthalmology , Volume 91 (1) – Jan 1, 1974

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Publisher
American Medical Association
Copyright
Copyright © 1974 American Medical Association. All Rights Reserved.
ISSN
0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1974.03900060015004
Publisher site
See Article on Publisher Site

Abstract

Abstract Brown-black pigmentation of hydrophilic lenses worn by three patients occurred within two months after concurrent epinephrine compound therapy was begun. In one case, dense pigmentation occurred in less than two weeks. Although no ocular damage resulted, considerable emotional trauma was experienced by one patient and his family prior to diagnosis of his apparently "black eye." In all cases the lenses were discarded. References 1. Löwenstein A: Künstliche Hervorrufung melanotischer Geschwülstchen in der Bindehaut . Ber Dtsch Ophthalmol Ges 46:439-441, 1927. 2. Veirs BR, McGrew JC: Ocular complications from topical epinephrine therapy of glaucoma . Eye Ear Nose Throat Mon 42:46-52, 1963. 3. Corwin ME, Spencer WH: Conjunctival melanin deposits, a side-effect of topical epinephrine therapy . Arch Ophthalmol 69:317-321, 1963.Crossref 4. Blobner E: Hornhautverfärbung durch ein Adrenalin präparat . Klin Monatsbl Augenheilkd 100:758-763, 1938. 5. Reinecke RD, Kuwabara T: Corneal deposits secondary to topical epinephrine . Am J Ophthalmol 70:170-172, 1963. 6. Ferry AP, Zimmerman LE: Black cornea: A complication of topical use of epinephrine . Am J Ophthalmol 58:205-210, 1964. 7. Cleasby G, Donaldson DD: Epinephrine pigmentation of the cornea . Arch Ophthalmol 78:74-75, 1967.Crossref 8. Green WR, Kaufer GJ, Dubroff, S: Black cornea, a complication of topical use of epinephrine . Ophthalmologica 154:88-95, 1967.Crossref 9. Madge GE, Geeraets WJ, Guerry D III: Black cornea secondary to topical epinephrine . Am J Ophthalmol 71:402-405, 1971. 10. Johnson BL, Buerger GF: Black orbital bone . Arch Ophthalmol 88:400-403, 1972.Crossref 11. Ferry JF: Black prosthesis, a complication of the topical use of epinephrine . Am J Ophthalmol 64:162, 1967. 12. Krejci L, Harrison R: Corneal pigment deposits from topically administered epinephrine: Experimental production . Arch Ophthalmol 82:836-839, 1969.Crossref

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Jan 1, 1974

References