Abstract In 1954 a report was published describing bilateral adrenalectomy for patients with severe hypertension.1,2 These operations were performed in what now can be termed the "pre-drug era," when the effectiveness of hypotensive drugs was not established. Consequently, the follow-up studies are made on a group of nine patients whose postoperative period is now four to six and one-half years. Obviously, when drugs became available, adrenalectomy was abandoned because one must induce hypoadrenalism to accomplish surgical relief by adrenalectomy. The hypoadrenalism is a major illness in itself, and the operation must not be used except for patients with severe hypertension whose tension is uncontrollable by other means. A few patients were subjected to bilateral adrenalectomy in the "post-drug era" when the drugs failed to invoke a desirable lowering of the blood pressure, but the surgical results were not good because most of the patients were too ill then to tolerate References 1. Bowers, R. F.: Bilateral Adrenalectomy for Severe Hypertension , J. A. M. A. 154:394-397 ( (Jan. 30) ) 1954.Crossref 2. Bowers, R. F.; Knox, F. H., Jr., and Gendel, B. R.: Adrenalectomy for Hypertension: Advantages of the Anterior Abdominal Approach , Surgery 34:664-671 ( (Oct.) ) 1953.
A.M.A. Archives Surgery – American Medical Association
Published: Nov 1, 1958
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