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Administration of Antitoxin.

Administration of Antitoxin. Fairfield, Iowa, Dec. 5, 1896. To the Editor: —In view of the occasional fatal effects of diphtheria antitoxin and the rapidity with which death occurs in these cases, I would suggest the advisability of dividing the administration of the desired dose into several stages at intervals of several minutes between the stages, giving but a fraction of the entire dose at each stage. Tentatively I propose one-fourth, or less, of the intended dose at each stage of the injection, letting an interval of five or preferably ten minutes elapse between the stages of the injection. I do not conceive it would be desirable to withdraw the syringe and re-introduce it when interstages are not longer than ten minutes, but the needle can remain introduced until the injection of the entire dose is effected. In case dying from the antitoxin, fatal collapse has usually resulted within five minutes from the time http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Administration of Antitoxin.

JAMA , Volume XXVII (24) – Dec 12, 1896

Administration of Antitoxin.

Abstract


Fairfield, Iowa, Dec. 5, 1896.

To the Editor:
—In view of the occasional fatal effects of diphtheria antitoxin and the rapidity with which death occurs in these cases, I would suggest the advisability of dividing the administration of the desired dose into several stages at intervals of several minutes between the stages, giving but a fraction of the entire dose at each stage.
Tentatively I propose one-fourth, or less, of the intended dose...
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Publisher
American Medical Association
Copyright
Copyright © 1896 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.1896.02431020037012
Publisher site
See Article on Publisher Site

Abstract

Fairfield, Iowa, Dec. 5, 1896. To the Editor: —In view of the occasional fatal effects of diphtheria antitoxin and the rapidity with which death occurs in these cases, I would suggest the advisability of dividing the administration of the desired dose into several stages at intervals of several minutes between the stages, giving but a fraction of the entire dose at each stage. Tentatively I propose one-fourth, or less, of the intended dose at each stage of the injection, letting an interval of five or preferably ten minutes elapse between the stages of the injection. I do not conceive it would be desirable to withdraw the syringe and re-introduce it when interstages are not longer than ten minutes, but the needle can remain introduced until the injection of the entire dose is effected. In case dying from the antitoxin, fatal collapse has usually resulted within five minutes from the time

Journal

JAMAAmerican Medical Association

Published: Dec 12, 1896

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