Abstract A series of 28 patients with an adenoid cystic carcinoma of the maxilla were treated at the Netherlands Cancer Institute. By observing these patients for a very long period of time, the poor prognosis confirms the findings in the literature. Some doubt is thrown on the applicability of the concept of complete removal of the tumor, particularly in the diagnosing phase. For a possible curative effect, the suggestion is made to treat these adenoid cystic carcinoma patients with a "three modality therapy." This combination therapy includes regional infusion with fluorouracil, followed by maxillary resection, sequentially followed by radiotherapy. The "inoperable" group must be treated with only radiotherapy for a palliative effect. References 1. Evans RW, Cruickshank AH: Adenocystic Carcinoma, Epithelial Tumours of the Salivary Glands . London, WB Saunders Co, 1970. 2. Ranger D, Thackray AC, Lucas RB: Mucous gland tumors . Br J Cancer 10:1, 1956.Crossref 3. Foot FW, Frazell MD: Adeno Carcinoma, Tumors of the Major Salivary Glands . Washington, DC, Armed Forces Institute of Pathology 1954. 4. Harrison K: A study of ectopic mixed salivary tumours . Ann Roy Coll Surg Engl 18:99-104, 1956. 5. Moran JJ, Becker SM, Brady LW, et al: Adenoid cystic carcinoma: Clinicopathological study . Cancer 14:1235-1250, 1961.Crossref 6. Bumsted WD: Cylindroma . Oral Surg 8:546-551, 1955.Crossref 7. Stewart J: Carcinoma of salivary glands showing the cylindroma pattern . Br J Surg 49:241-245, 1961.Crossref 8. Eneroth CM, Hjertman L, Moberger G: Adenoid cystic carcinoma of the palate . Acta Otolaryngol (Stockh) 66:248-260, 1968.Crossref 9. Eby LS, Johnson DS, Baker HW: Adenoid cystic carcinoma of the head and neck . Cancer 29:1160-1168, 1972.Crossref 10. Struben WH, Hampe JF: Cylindromas of the upper respiratory tract . J Laryngol 11:722-731, 1959.Crossref 11. Langezaal OAM, Delemarre JFM, van Slooten EA: Malignant epithelial tumors of the parotid gland . Arch Chir Neerl 25:441-456, 1973. 12. Ullik R: Zur Entwicklung der Kiefer Chirurgie . Z Stom 55:67-77, 1949. 13. King J, Fletcher H: Malignant tumors of the major salivary glands . Radiology 100:381-389, 1971.Crossref
Archives of Otolaryngology – American Medical Association
Published: Dec 1, 1974
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