Abstract Of 134 patients with adenoid cystic carcinoma, 58% of the neoplasms occurred in the minor salivary glands, and 42% in the major salivary glands. Metastases and recurrences occurred in 67% of 56 patients in the major salivary gland group, and in 92% of 78 patients in the minor salivary gland group. A major surgical ablative procedure is the treatment of choice in the potentially resectable primary and recurrent tumors. Failure at this stage usually means incurability, but not necessarily failure at good palliation. Irradiation proved to be an effective and indispensable adjunct in management of the majority of these patients. Of the entire group, 25 (20%) were living and free of disease after 15 or more years. The major salivary gland patients enjoyed a significantly better prognosis. References 1. Eby LS, Johnson DS, Baker HW: Adenoid cystic carcinoma of the head and neck . Cancer 29:1160-1168, 1972.Crossref 2. Eneroth CM, Hjertman L, Moberger G: Adenoid cystic carcinoma of the palate . Acta Otolaryngol 66:248-260, 1968.Crossref 3. Foote FW Jr, Frazell EL: Tumors of the Major Salivary Glands. Atlas of Tumor Pathology , section 4, (part 11) , 1954. 4. Leafstedt SW, Gaeta JF, Sako K, et al: Adenoid cystic carcinoma of major and minor salivary glands . Am J Surg 122:756-762, 1971.Crossref 5. Moran JJ, Becker SM, Brady LW, et al: Adenoid cystic carcinoma: A clinicopathological study . Cancer 14:1235-1250, 1961.Crossref 6. Pulec JL, Parkhill EM, Devine KD: Adenoid cystic carcinoma (cylindroma) of the external auditory canal . Trans Am Acad Ophthalmol Otolaryngol 67:673-694, 1963. 7. Stewart J: Carcinoma of salivary glands showing the cylindroma pattern . Br J Surg 49:241-245, 1961.Crossref
Archives of Otolaryngology – American Medical Association
Published: Aug 1, 1974
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