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Addressing the Sexually Transmitted Infection and HIV Syndemic

Addressing the Sexually Transmitted Infection and HIV Syndemic Opinion EDITORIAL Addressing the Sexually Transmitted Infection and HIV Syndemic Monica Gandhi, MD, MPH; Matthew A. Spinelli, MD; Kenneth H. Mayer, MD The HIV and sexually transmitted infection (STI) epidemics, would have otherwise gone undetected by patients and pub- lic health systems. which have always been and will always be intertwined, are at an inflection point. Two scientific advancements over the In the subpopulation in this study (n = 1378), the unad- last decade have substantially influenced the sexual health of justed incidence of any STI increased significantly (incidence people living with HIV and individuals at risk for HIV. rate ratio, 1.41 [95% CI, 1.29-1.56]) during PrEPX, from 69.5 per First, Undetectable equals Untransmittable (U = U) is an 100 person-years in the preenrollment period to 98.4 per 100 important public health campaign that supports the findings person-years during follow-up. However, when the authors ad- that individuals with a suppressed viral load do not transmit justed for increased testing frequency among participants, STI HIV despite condomless sex. U = U builds on the findings of incidence attenuated to a 12% increase (adjusted incidence rate several large trials that have demonstrated the remarkable ratio, 1.12 [95% CI, 1.02-1.23]). This finding http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png JAMA American Medical Association

Addressing the Sexually Transmitted Infection and HIV Syndemic

JAMA , Volume 321 (14) – Apr 9, 2019

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Publisher
American Medical Association
Copyright
Copyright 2019 American Medical Association. All Rights Reserved.
ISSN
0098-7484
eISSN
1538-3598
DOI
10.1001/jama.2019.2945
Publisher site
See Article on Publisher Site

Abstract

Opinion EDITORIAL Addressing the Sexually Transmitted Infection and HIV Syndemic Monica Gandhi, MD, MPH; Matthew A. Spinelli, MD; Kenneth H. Mayer, MD The HIV and sexually transmitted infection (STI) epidemics, would have otherwise gone undetected by patients and pub- lic health systems. which have always been and will always be intertwined, are at an inflection point. Two scientific advancements over the In the subpopulation in this study (n = 1378), the unad- last decade have substantially influenced the sexual health of justed incidence of any STI increased significantly (incidence people living with HIV and individuals at risk for HIV. rate ratio, 1.41 [95% CI, 1.29-1.56]) during PrEPX, from 69.5 per First, Undetectable equals Untransmittable (U = U) is an 100 person-years in the preenrollment period to 98.4 per 100 important public health campaign that supports the findings person-years during follow-up. However, when the authors ad- that individuals with a suppressed viral load do not transmit justed for increased testing frequency among participants, STI HIV despite condomless sex. U = U builds on the findings of incidence attenuated to a 12% increase (adjusted incidence rate several large trials that have demonstrated the remarkable ratio, 1.12 [95% CI, 1.02-1.23]). This finding

Journal

JAMAAmerican Medical Association

Published: Apr 9, 2019

References