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ACUTE SUPPURATIVE OTITIS MEDIA: A REVIEW OF CASES ENCOUNTERED DURING A FIVE YEAR PERIOD

ACUTE SUPPURATIVE OTITIS MEDIA: A REVIEW OF CASES ENCOUNTERED DURING A FIVE YEAR PERIOD Abstract In 1935 Domagk described his experiments with a sulfanilamide compound and inspired the medical profession to renewed activity in combating bacterial infections with chemotherapy. About a year later Colebrook proclaimed that sulfanilamide was practically a specific for infections due to the beta type of hemolytic streptococcus. Since that time sulfanilamide has been widely used against infections caused by a variety of organisms. Derivatives of the drug have been developed and, like the parent substance, have also been extensively used. Much has been written on this phase of chemotherapy, not only to advocate the use of sulfanilamide and its derivatives, but also to point out possible dangers associated with their administration. It was only natural that sulfanilamide should have received an early and general reception in the field of otolaryngology, where the hemolytic streptococcus plays such a prominent part in disease. Since the introduction of this drug and its derivatives there References 1. Maybaum, J. L., and Druss, J. G.: Otitic Infections Due to the Pneumococcus Type III , Arch. Otolaryng. 30:21 ( (July) ) 1939.Crossref 2. In 1 patient who had a simple mastoidectomy in December 1939, what was considered a new infection developed in April 1940, and the patient died of meningitis. The organism found in the culture from the ear and in that from the cerebrospinal fluid was the pneumococcus type XXXII. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Otolaryngology American Medical Association

ACUTE SUPPURATIVE OTITIS MEDIA: A REVIEW OF CASES ENCOUNTERED DURING A FIVE YEAR PERIOD

Archives of Otolaryngology , Volume 33 (5) – May 1, 1941

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Publisher
American Medical Association
Copyright
Copyright © 1941 American Medical Association. All Rights Reserved.
ISSN
0003-9977
DOI
10.1001/archotol.1941.00660030744007
Publisher site
See Article on Publisher Site

Abstract

Abstract In 1935 Domagk described his experiments with a sulfanilamide compound and inspired the medical profession to renewed activity in combating bacterial infections with chemotherapy. About a year later Colebrook proclaimed that sulfanilamide was practically a specific for infections due to the beta type of hemolytic streptococcus. Since that time sulfanilamide has been widely used against infections caused by a variety of organisms. Derivatives of the drug have been developed and, like the parent substance, have also been extensively used. Much has been written on this phase of chemotherapy, not only to advocate the use of sulfanilamide and its derivatives, but also to point out possible dangers associated with their administration. It was only natural that sulfanilamide should have received an early and general reception in the field of otolaryngology, where the hemolytic streptococcus plays such a prominent part in disease. Since the introduction of this drug and its derivatives there References 1. Maybaum, J. L., and Druss, J. G.: Otitic Infections Due to the Pneumococcus Type III , Arch. Otolaryng. 30:21 ( (July) ) 1939.Crossref 2. In 1 patient who had a simple mastoidectomy in December 1939, what was considered a new infection developed in April 1940, and the patient died of meningitis. The organism found in the culture from the ear and in that from the cerebrospinal fluid was the pneumococcus type XXXII.

Journal

Archives of OtolaryngologyAmerican Medical Association

Published: May 1, 1941

References