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ACUTE RETROBULBAR NEURITIS AS A MANIFESTATION OF ACUTE LOCALIZED TISSUE ANOXIA: TREATMENT WITH VASODILATORS

ACUTE RETROBULBAR NEURITIS AS A MANIFESTATION OF ACUTE LOCALIZED TISSUE ANOXIA: TREATMENT WITH... Abstract Acute retrobulbar neuritis is a disease of the optic nerve, chiasm or tract usually characterized by marked and sudden loss of sight in one or both eyes, with a central or paracentral scotoma. Rarely the fields are contracted. Occasionally there is pain on movement of the eye. The pupil often shows hippus. The fundus may be normal, or there may be venous congestion, optic neuritis or papilledema of as much as 6 D. When the lesion is close to the globe the changes in the disk are pronounced and the condition is called optic neuritis. When the lesion is behind the entrance of the retinal vessels into the optic nerve the fundus is usually normal and the condition is called retrobulbar neuritis. Although the two conditions are treated as separate and distinct diseases in the textbooks, the differences between acute optic and acute retrobulbar neuritis are quantitative rather than qualitative References 1. Much, V., and Hüppi, A.: Klin. Monatsbl. f. Augenh. 93:333 ( (Sept.) ) 1934. 2. Butler, T. H.: Brit. J. Ophth. 10:184 ( (April) ) 1926.Crossref 3. Juhasz-Schäffer, A.: Klin. Wchnschr. 11:1232 ( (July 16) ) 1932.Crossref 4. Kagan, Y. A.: Sovet. vestnik oftal. 5:503, 1934. 5. Masson, C. B.: Bull. Neurol. Inst. New York 3:190 ( (June) ) 1933. 6. Monbrun, A.; Richet, C., and Facquet, J.: Arch. d'opht. 49:697 ( (Nov.) ) 1932. 7. Puscariu, E.: Brit. J. Ophth. 21:599 ( (Nov.) ) 1937.Crossref 8. Thies: Klin. Monatsbl. f. Augenh. 88:855 ( (June) ) 1932 9. abstracted, Arch. Ophth. 9:500 ( (March) ) 1933. 10. Duggan, W. F.: Use of Vasodilators in Treatment of Retrobulbar Neuritis , Arch. Ophth. 16:380 ( (Sept.) ) 1936.Crossref 11. Lillie, W. I.: Am. J. Ophth. 17:110 ( (Feb.) ) 1934. 12. Snell, A. C.: New York State J. Med. 33:370 ( (March 15) ) 1933. 13. Wilson, G., and Darkes, W. F.: Unilateral Choked Disk Due to Chronic Tonsillar Infection , J. A. M. A. 100:1233 ( (April 22) ) 1933.Crossref 14. Harry, P. A.: Brit. J. Ophth. 6:216 ( (May) ) 1922.Crossref 15. Bulson, A. E.: Choked Disk (Papilledema) Due to Disease of Sphenoidal Sinus , J. A. M. A. 97:926 ( (Sept. 26) ) 1931.Crossref 16. Feigenbaum, A., and Salzberger, M.: Folia oto-laryng. orient. 1:50 ( (Oct.) ) 1932. 17. Cormack, H. S., and Anderson, L. A. P.: Brit. J. Ophth. 18:167 ( (March) ) 1934.Crossref 18. Hasabe: Acta Soc. ophth. japon. 38:102 ( (July) ) 1934. 19. Suzuki: Acta Soc. ophth. japon. (July) 39:219, 1936 20. abstracted, Zentralbl. f. d. ges. Ophth. 36:415, 1936. 21. Shannon, C. E. G.: Bitemporal Paracentral Scotoma , Arch. Ophth. 6:544 ( (Oct.) ) 1931.Crossref 22. Clay, G. E., and Baird, J. M.: Unclassified Type of Optic Neuritis: Report of Cases , Arch. Ophth. 18:777 ( (Nov.) ) 1937.Crossref 23. Isenschmid, R., and Kunz, E.: Schweiz. med. Wchnschr. 65:530 ( (June 8) ) 1935. 24. Bucy, P. C.: Toxic Optic Neuritis Resulting from Sulfanilamide , J. A. M. A. 109:1007 ( (Sept. 25) ) 1937.Crossref 25. (a) Barr, A. S.: Am. J. Ophth. 17:396 ( (May) ) 1934. 26. (b) Knapp, A.: Medical Ophthalmology , Philadelphia, P. Blakiston's Son & Co., 1918, pp. 407-409. 27. (c) Moore, R. F.: Medical Ophthalmology , ed. 2, London, J. & A. Churchill, 1925, pp. 109-111. 28. Besso, M. G.: Rassegna ital. d'ottal. 6:381 ( (July-Aug.) ) 1937 29. abstracted, Am. J. Ophth. 21:341 ( (March) ) 1938. 30. Kahoun, S.: Českoslov. opht. 3:122, 1937 31. abstracted, Am. J. Ophth. 21:340 ( (March) ) 1938. 32. Bedell, A.: New York State J. Med. 33:361 ( (March 15) ) 1933. 33. Campbell, E. H.: Relationship of Sinusitis to Optic and Retrobulbar Neuritis, with Special Reference to Etiology and Treatment , Arch. Ophth. 16:236 ( (Aug.) ) 1936.Crossref 34. Hoople, G. D.: New York State J. Med. 33:365 ( (March 15) ) 1933. 35. Moore,20c p. 166. 36. Benedict, W. L.: Retrobulbar Neuritis and Disease of Nasal Accessory Sinuses , Arch. Ophth. 9:893 ( (June) ) 1933.Crossref 37. Reimann, H. A., and Havens, W. P.: Focal Infection and Systemic Disease: A Critical Appraisal , J. A. M. A. 114:1 ( (Jan. 6) ) 1940. 38. Moon, V. : Shock and Related Capillary Phenomena , New York, Oxford University Press, 1938. 39. In eighteen attacks, intravenous injections of sodium nitrite (0.1 Gm.) were given. The average treatment was eight daily injections. One patient received only four daily injections, and 1 received eighteen daily injections. One patient received injections twice daily, and 1 received ten injections in eighteen days. In 4 attacks, intramuscular injections of acetylcholine (0.1 Gm.) were used. In 3 instances, daily injections were given for five, six and nine days. The other patient received three injections in ten days. In 1 attack, three daily inhalations of amyl nitrite was the only therapy used. In 2 attacks (cases 4 and 25) injections of sodium nitrite and inhalations of amyl nitrite at home were used. In 2 attacks (cases 17 and 23) intravenous injections of sodium nitrite and one or two retrobulbar injections of acetylcholine were given. 40. Kennedy, F.: New York State J. Med. 36:469 ( (April 1) ) 1936. 41. Putnam, T. J.: Science 80:295 ( (Sept. 28) ) 1934.Crossref 42. Putnam, T. J.: Lesions of Encephalomyelitis and Multiple Sclerosis: Venous Thombosis as the Primary Alteration , J. A. M. A. 108:1477 ( (May 1) ) 1937.Crossref 43. Simon, B., and Solomon, P.: Multiple Sclerosis , Arch. Neurol. & Psychiat. 34:1286 ( (Dec.) ) 1935. 44. Horton, B.; Brown, G., and Roth, G.: Hypersensitiveness to Cold , J. A. M. A. 107:1263 ( (Oct. 17) ) 1936. 45. Topley, W. C.: An Outline of Immunity , Baltimore, William Wood & Company, 1933. 46. Horder: Brit. M. J. 1:632 ( (March 25) ) 1939. 47. Mautner, H., and Pick, E. P., cited by Sollmann, T. H.: A Manual of Pharmacology , ed. 2, Philadelphia, W. B. Saunders Company, 1922, p. 446. 48. Best, C. H., and McHenry, E. W.: Physiol. Rev. 11:371 ( (Oct.) ) 1931. 49. Cross, R.: Tr. Ophth. Soc. U. Kingdom 33:43, 1913. 50. Sourdille, C.: Clin. opht. 6:280, 1900 51. abstracted, Arch. Ophth. 30:191, 1901. 52. Schieck, F.: Arch. f. Ophth. 71:466, 1909. 53. Aubaret, E., and Sédan, J.: Clin. opht. 32:255, 1928. 54. de Saint-Martin: Ann. d'ocul. 168:102 ( (Feb.) ) 1931. 55. Hartmann, E., and Parfonry, J.: Bull. Soc. d'opht. de Paris , (February) 1934, p. 56. 56. Bedell, A.: New York State J. Med. 36:959 ( (July 1) ) 1936. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Ophthalmology American Medical Association

ACUTE RETROBULBAR NEURITIS AS A MANIFESTATION OF ACUTE LOCALIZED TISSUE ANOXIA: TREATMENT WITH VASODILATORS

Archives of Ophthalmology , Volume 25 (2) – Feb 1, 1941

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American Medical Association
Copyright
Copyright © 1941 American Medical Association. All Rights Reserved.
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0003-9950
eISSN
1538-3687
DOI
10.1001/archopht.1941.00870080123009
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Abstract

Abstract Acute retrobulbar neuritis is a disease of the optic nerve, chiasm or tract usually characterized by marked and sudden loss of sight in one or both eyes, with a central or paracentral scotoma. Rarely the fields are contracted. Occasionally there is pain on movement of the eye. The pupil often shows hippus. The fundus may be normal, or there may be venous congestion, optic neuritis or papilledema of as much as 6 D. When the lesion is close to the globe the changes in the disk are pronounced and the condition is called optic neuritis. When the lesion is behind the entrance of the retinal vessels into the optic nerve the fundus is usually normal and the condition is called retrobulbar neuritis. Although the two conditions are treated as separate and distinct diseases in the textbooks, the differences between acute optic and acute retrobulbar neuritis are quantitative rather than qualitative References 1. Much, V., and Hüppi, A.: Klin. Monatsbl. f. Augenh. 93:333 ( (Sept.) ) 1934. 2. Butler, T. H.: Brit. J. Ophth. 10:184 ( (April) ) 1926.Crossref 3. Juhasz-Schäffer, A.: Klin. Wchnschr. 11:1232 ( (July 16) ) 1932.Crossref 4. Kagan, Y. A.: Sovet. vestnik oftal. 5:503, 1934. 5. Masson, C. B.: Bull. Neurol. Inst. New York 3:190 ( (June) ) 1933. 6. Monbrun, A.; Richet, C., and Facquet, J.: Arch. d'opht. 49:697 ( (Nov.) ) 1932. 7. Puscariu, E.: Brit. J. Ophth. 21:599 ( (Nov.) ) 1937.Crossref 8. Thies: Klin. Monatsbl. f. Augenh. 88:855 ( (June) ) 1932 9. abstracted, Arch. Ophth. 9:500 ( (March) ) 1933. 10. Duggan, W. F.: Use of Vasodilators in Treatment of Retrobulbar Neuritis , Arch. Ophth. 16:380 ( (Sept.) ) 1936.Crossref 11. Lillie, W. I.: Am. J. Ophth. 17:110 ( (Feb.) ) 1934. 12. Snell, A. C.: New York State J. Med. 33:370 ( (March 15) ) 1933. 13. Wilson, G., and Darkes, W. F.: Unilateral Choked Disk Due to Chronic Tonsillar Infection , J. A. M. A. 100:1233 ( (April 22) ) 1933.Crossref 14. Harry, P. A.: Brit. J. Ophth. 6:216 ( (May) ) 1922.Crossref 15. Bulson, A. E.: Choked Disk (Papilledema) Due to Disease of Sphenoidal Sinus , J. A. M. A. 97:926 ( (Sept. 26) ) 1931.Crossref 16. Feigenbaum, A., and Salzberger, M.: Folia oto-laryng. orient. 1:50 ( (Oct.) ) 1932. 17. Cormack, H. S., and Anderson, L. A. P.: Brit. J. Ophth. 18:167 ( (March) ) 1934.Crossref 18. Hasabe: Acta Soc. ophth. japon. 38:102 ( (July) ) 1934. 19. Suzuki: Acta Soc. ophth. japon. (July) 39:219, 1936 20. abstracted, Zentralbl. f. d. ges. Ophth. 36:415, 1936. 21. Shannon, C. E. G.: Bitemporal Paracentral Scotoma , Arch. Ophth. 6:544 ( (Oct.) ) 1931.Crossref 22. Clay, G. E., and Baird, J. M.: Unclassified Type of Optic Neuritis: Report of Cases , Arch. Ophth. 18:777 ( (Nov.) ) 1937.Crossref 23. Isenschmid, R., and Kunz, E.: Schweiz. med. Wchnschr. 65:530 ( (June 8) ) 1935. 24. Bucy, P. C.: Toxic Optic Neuritis Resulting from Sulfanilamide , J. A. M. A. 109:1007 ( (Sept. 25) ) 1937.Crossref 25. (a) Barr, A. S.: Am. J. Ophth. 17:396 ( (May) ) 1934. 26. (b) Knapp, A.: Medical Ophthalmology , Philadelphia, P. Blakiston's Son & Co., 1918, pp. 407-409. 27. (c) Moore, R. F.: Medical Ophthalmology , ed. 2, London, J. & A. Churchill, 1925, pp. 109-111. 28. Besso, M. G.: Rassegna ital. d'ottal. 6:381 ( (July-Aug.) ) 1937 29. abstracted, Am. J. Ophth. 21:341 ( (March) ) 1938. 30. Kahoun, S.: Českoslov. opht. 3:122, 1937 31. abstracted, Am. J. Ophth. 21:340 ( (March) ) 1938. 32. Bedell, A.: New York State J. Med. 33:361 ( (March 15) ) 1933. 33. Campbell, E. H.: Relationship of Sinusitis to Optic and Retrobulbar Neuritis, with Special Reference to Etiology and Treatment , Arch. Ophth. 16:236 ( (Aug.) ) 1936.Crossref 34. Hoople, G. D.: New York State J. Med. 33:365 ( (March 15) ) 1933. 35. Moore,20c p. 166. 36. Benedict, W. L.: Retrobulbar Neuritis and Disease of Nasal Accessory Sinuses , Arch. Ophth. 9:893 ( (June) ) 1933.Crossref 37. Reimann, H. A., and Havens, W. P.: Focal Infection and Systemic Disease: A Critical Appraisal , J. A. M. A. 114:1 ( (Jan. 6) ) 1940. 38. Moon, V. : Shock and Related Capillary Phenomena , New York, Oxford University Press, 1938. 39. In eighteen attacks, intravenous injections of sodium nitrite (0.1 Gm.) were given. The average treatment was eight daily injections. One patient received only four daily injections, and 1 received eighteen daily injections. One patient received injections twice daily, and 1 received ten injections in eighteen days. In 4 attacks, intramuscular injections of acetylcholine (0.1 Gm.) were used. In 3 instances, daily injections were given for five, six and nine days. The other patient received three injections in ten days. In 1 attack, three daily inhalations of amyl nitrite was the only therapy used. In 2 attacks (cases 4 and 25) injections of sodium nitrite and inhalations of amyl nitrite at home were used. In 2 attacks (cases 17 and 23) intravenous injections of sodium nitrite and one or two retrobulbar injections of acetylcholine were given. 40. Kennedy, F.: New York State J. Med. 36:469 ( (April 1) ) 1936. 41. Putnam, T. J.: Science 80:295 ( (Sept. 28) ) 1934.Crossref 42. Putnam, T. J.: Lesions of Encephalomyelitis and Multiple Sclerosis: Venous Thombosis as the Primary Alteration , J. A. M. A. 108:1477 ( (May 1) ) 1937.Crossref 43. Simon, B., and Solomon, P.: Multiple Sclerosis , Arch. Neurol. & Psychiat. 34:1286 ( (Dec.) ) 1935. 44. Horton, B.; Brown, G., and Roth, G.: Hypersensitiveness to Cold , J. A. M. A. 107:1263 ( (Oct. 17) ) 1936. 45. Topley, W. C.: An Outline of Immunity , Baltimore, William Wood & Company, 1933. 46. Horder: Brit. M. J. 1:632 ( (March 25) ) 1939. 47. Mautner, H., and Pick, E. P., cited by Sollmann, T. H.: A Manual of Pharmacology , ed. 2, Philadelphia, W. B. Saunders Company, 1922, p. 446. 48. Best, C. H., and McHenry, E. W.: Physiol. Rev. 11:371 ( (Oct.) ) 1931. 49. Cross, R.: Tr. Ophth. Soc. U. Kingdom 33:43, 1913. 50. Sourdille, C.: Clin. opht. 6:280, 1900 51. abstracted, Arch. Ophth. 30:191, 1901. 52. Schieck, F.: Arch. f. Ophth. 71:466, 1909. 53. Aubaret, E., and Sédan, J.: Clin. opht. 32:255, 1928. 54. de Saint-Martin: Ann. d'ocul. 168:102 ( (Feb.) ) 1931. 55. Hartmann, E., and Parfonry, J.: Bull. Soc. d'opht. de Paris , (February) 1934, p. 56. 56. Bedell, A.: New York State J. Med. 36:959 ( (July 1) ) 1936.

Journal

Archives of OphthalmologyAmerican Medical Association

Published: Feb 1, 1941

References